Sino Biological/Vimentin Protein, Human, Recombinant (His Tag)/1/10028-H08B
商品编号：
10028-H08B
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Vimentin Protein, Human, Recombinant (His Tag): Product Information
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 1.0="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the human VIM (Met1-Glu466) (P08670) was expressed with a C-terminal polyhistidine tag.
Accession#
P08670
Expressed Host
Baculovirus-Insect Cells
Species
Human
Predicted N Terminal
Met 1
Molecule Mass
The secreted recombinant human VIM consists of 477 amino acids and predicts a molecular mass of 55.11 KDa.
Formulation
Lyophilized from sterile 40% acetonitrile, 0.1% TFAPlease contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Vimentin Protein, Human, Recombinant (His Tag): Images
Vimentin Protein, Human, Recombinant (His Tag): Synonyms
CTRCT30 Protein, Human; HEL113 Protein, Human
Vimentin Background Information
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. Therefore, in general, it is accepted that vimentin is the cytoskeletal component responsible for maintaining cell integrity. Vimentin is also responsible for stabilizing cytoskeletal interactions. It is found that vimentin control the transport of low-density lipoprotein. It has been used as a sarcoma tumor marker to identify mesenchyme.
Full Name
vimentin
References
- Russell RL, et al. (2001) Uridine phosphorylase association with vimentin. Intracellular distribution and localization. J Biol Chem. 276(16):13302-7.
- Moinova, et al. (2012) Aberrant Vimentin Methylation is Characteristic of Upper GI Pathologies. Cancer Epidemiology Biomarkers Prev. 21(4):594-600.
- Leader M, et al. (1987) Vimentin: an evaluation of its role as a tumour marker. Histopathology. 11(1):63-72.
- Extracellular vimentin modulates human dendritic cell activationAuthorYu, MB;Guerra, J;Firek, A;Langridge, WHR;Year2018JournalMol. Immunol.Applicationcell-based (DC activation)PubMed ID: 30399492FoldedExpand
- Click RNA for Rapid Capture and Identification of Intracellular MicroRNA TargetsAuthorZhang, P;Fu, H;Du, S;Wang, F;Yang, J;Cai, W;Liu, D;Year2019JournalAnal. Chem.ApplicationbindingPubMed ID: 31714070FoldedExpand
- Vimentin-targeting AIEgen-peptide conjugates: Wash-free fluorescence detection of EMT-type cancer cells and tissuesAuthorWei, H;Yu, Y;Wang, Y;Ying, Z;Cheng, W;Tian, X;Kan, Q;Year2020JournalSensors and Actuators B: ChemicalApplicationfluorescence titration; confocalFoldedExpand
- Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibitionAuthorRoy, S;Kapoor, A;Zhu, F;Mukhopadhyay, R;Ghosh, AK;Lee, H;Mazzone, J;Posner, GH;Arav-Boger, R;Year2020JournalJ. Biol. Chem.ApplicationsubstratePubMed ID: 32855235FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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