Sino Biological/ENO1 Protein, Human, Recombinant (His Tag)/1/11554-H07E
商品编号：
11554-H07E
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
ENO1 Protein, Human, Recombinant (His Tag): Product Information
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the human ENO1 (P06733-1) (Met 1-Lys 434) was expressed, with a polyhistide tag at the N-terminus.
Accession#
P06733-1
Expressed Host
E. coli
Species
Human
Predicted N Terminal
Met
Molecule Mass
The recombinant human ENO1 consisting of 450 amino acids and has a calculated molecular mass of 49.3 kDa. It migrates as an 47 kDa band in SDS-PAGE under reducing conditions as predicted.
Formulation
Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.5Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
ENO1 Protein, Human, Recombinant (His Tag): Images
ENO1 Protein, Human, Recombinant (His Tag): Synonyms
ENO1L1 Protein, Human; HEL-S-17 Protein, Human; MPB1 Protein, Human; NNE Protein, Human; PPH Protein, Human
ENO1 Background Information
The ENO1 gene encodes a multifunctional enzyme that has been identified as a keycomponent of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make the primary culture follicle granulosa cells in vitro improve progesterone secretion. The over-expression of ENO1 protein can enhance the abilities of proliferation and migration in gastric cancer cells of AGS, which indicates that ENO1 may be an important potential tumor-marker associated with the development of gastric cancer. ENO1 and GPI can be used as markers of human sperm freezability before starting the cryopreservation procedure. The inhibition of ENO1 expression may be a novel strategy for therapy for NHLs patients, and it may be a target for drug resistance.
Full Name
enolase 1, (alpha)
References
- Capello M, et al. (2011) a-Enolase: a promising therapeutic and diagnostic tumor target. FEBS J. 278(7): 1064-74.
- Kang HJ, et al. (2008) Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme. Acta Crystallogr D Biol Crystallogr. 64(Pt 6): 651-7.
- Lopez-Alemany R, et al. (2005) Alpha-enolase plasminogen receptor in myogenesis. Front Biosci. 10: 30-6.
- Ejeskdr K, et al. (2005) Introduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell death. BMC Cancer. 5: 161.
Rat ENO1 Proteins
- ENO1 Protein, Rat, Recombinant (His Tag)80578-R07E
- Mitochondrial binding of α-enolase stabilizes mitochondrial membrane: its role in doxorubicin-induced cardiomyocyte apoptosisAuthorGao, S;Li, H;Cai, Y;Ye, JT;Liu, ZP;Lu, J;Huang, XY;Feng, XJ;Gao, H;Chen, SR;Li, M;Liu, PQ;Year2014JournalArch. Biochem. Biophys.PubMed ID: 24361255FoldedExpand
- A Dimerization Function in the Intrinsically Disordered N-Terminal Region of SrcAuthorSpassov, DS;Ruiz-Saenz, A;Piple, A;Moasser, MM;Year2018JournalCell RepApplicationsubstratePubMed ID: 30304684FoldedExpand
- 自身免疫甲状腺炎患者焦虑, 抑郁自评测定及相关影响因素Author杨雅莉, ;张金花, ;秦娟, ;孙溶励, ;李静, ;单忠艳, ;Year2019Journal中国医科大学学报ApplicationELISA (diagnostic)FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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