Sino Biological/Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III, His Tag)/1/40543-V08H
商品编号：
40543-V08H
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III, His Tag): Product Information
Purity
> 90 % as determined by SDS-PAGE.
Endotoxin
< 1.0="" eu="" per="" μg="" protein="" as="" determined="" by="" the="" lal="">
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the Zika virus (strain Zika SPH2015) E / Envelope (domain III) (ALU33341.1) (Val593-Lys699) was expressed with a polyhistidine tag at the C-terminus.
Accession#
ALU33341.1
Expressed Host
HEK293 Cells
Species
ZIKV
Predicted N Terminal
Val 593
Molecule Mass
The recombinant Zika virus (strain Zika SPH2015) E / Envelope (domain III) consists of 118 amino acids and predicts a molecular mass of 13 kDa.
Formulation
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III, His Tag): Images
ZIKV Envelope Background Information
Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF. Domain III of the Zika envelope protein , likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.
References
- Marina Basarab specialty registrar. et al .Zika virus. BMJ 2016; 352:i1049 doi: 10.1136/bmj.i1049
- Pinto Júnior VL, et al. Zika virus: a review to clinicians, Acta Med Port 2015 Nov-Dec;28(6):760-765
- L Zammarchi, et al.Zika virus infection in a traveler returning to Europe from Brazil, March 2015
- Arturo Galindo-Fraga, et al. Zika virus: A new epidemic on our doorstep. Rev Inves Clin.2015, 67: 329-32
ZIKV ZIKV Envelope Proteins
- Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III, His Tag)40543-V08B1
- Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III, His Tag), Biotinylated40543-V08H-B
- Zika virus (ZIKV) (strain Zika SPH2015) prME protein ( His Tag)40543-V08B4
- Zika virus (strain Zika SPH2015) E / Envelope protein (Domain I, His & MBP Tag)40543-V10E
- Zika virus (ZIKV) (strain Zika SPH2016) ZIKV-E (Stem/anchor domain of flavivirus envelope glycoprotein E) protein (Fc Tag)40543-V02H3
- Zika virus (ZIKV) (strain Zika SPH2015) E / Envelope protein (aa 291-696, His Tag)40543-V08B5
- Zika virus (strain Zika SPH2015) E / Envelope protein (Domain III, His Tag)40543-V08Y
- Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III, Fc Tag)40543-V02H
- Deciphering Protein O-Glycosylation: Solid-Phase Chemoenzymatic Cleavage and EnrichmentAuthorYang, S;Onigman, P;Wu, WW;Sjogren, J;Nyhlen, H;Shen, RF;Cipollo, J;Year2018JournalAnal. Chem.ApplicationO-glycosylation analysisPubMed ID: 29936827FoldedExpand
- Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse modelAuthorNiu, X;Zhao, L;Qu, L;Yao, Z;Zhang, F;Yan, Q;Zhang, S;Liang, R;Chen, P;Luo, J;Xu, W;Lv, H;Liu, X;Lei, H;Yi, C;Li, P;Wang, Q;Wang, Y;Yu, L;Zhang, X;Bryan, LA;Davidson, E;Doranz, JB;Feng, L;Pan, W;Zhang, F;Chen, L;Year2019JournalEmerg Microbes InfectPubMed ID: 31130109FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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