Sino Biological/Carbonic anhydrase II Protein, Human, Recombinant (His Tag)/1/10478-H08E
商品编号：
10478-H08E
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Carbonic anhydrase II Protein, Human, Recombinant (His Tag): Product Information
Purity
> 96 % as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Activity
Measured by its esterase activity. The specific activity is >150 pmoles/min/μg.
Protein Construction
A DNA sequence encoding the human CA2 (NP_000058.1) (Met 1-Lys 260) was expressed, with a polyhistide tag at the C-terminus.
Accession#
NP_000058.1
Expressed Host
E. coli
Species
Human
Predicted N Terminal
Met 1
Molecule Mass
The recombinant human CA2 consisting of 266 amino acids and has a calculated molecular mass of 30 kDa as estimated in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile 20mM Tris 0.5M NaCl, pH 8.0Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Carbonic anhydrase II Protein, Human, Recombinant (His Tag): Images
Carbonic anhydrase II Protein, Human, Recombinant (His Tag): Synonyms
CA-II Protein, Human; CAC Protein, Human; CAII Protein, Human; Car2 Protein, Human; HEL-76 Protein, Human; HEL-S-282 Protein, Human
Carbonic anhydrase II Background Information
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase II is one of fourteen forms of human α carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.
Full Name
carbonic anhydrase II
References
- Lehtonen J, et al. (2004) Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family. The Journal of Biological Chemistry. 279: 2719-27.
- Lindskog S. (1997) Structure and mechanism of carbonic anhydrase. Pharmacology & Therapeutics. 74(1)：1-20．
- Lilias A, et al. (1972) Crystal Structure of Human Carbonic Anhydrase C. Nature new biology. 235: 131-7.
- Li XJ, et al. (2002) Carbonic Anhydrase II Binds to and Enhances Activity of the Na+/H+ Exchanger. The Journal of Biological Chemistry. 277: 36085-91.
Mouse Carbonic anhydrase II Proteins
- Carbonic anhydrase II Protein, Mouse, Recombinant (His Tag)50685-M08E
- Development and validation of new approaches for quantitative intermolecular interaction analysis by MicroScale Thermophoresis under near-native experimentalAuthorBartoschik, TA;Year2019JournalThesisPubMed ID: 31214999FoldedExpand
- Synthesis, Molecular Docking Analysis, and Carbonic Anhydrase Inhibitory Evaluations of Benzenesulfonamide Derivatives Containing ThiazolidinoneAuthorZhang, ZP;Yin, ZF;Li, JY;Wang, ZP;Wu, QJ;Wang, J;Liu, Y;Cheng, MS;Year2019JournalMoleculesApplicationenzymePubMed ID: 31262068FoldedExpand
- 5-[2-(N-(substituted phenyl) acetamide)] amino-1, 3, 4-thiadiazole -2-sulfonamides as selective carbonic anhydrase II inhibitor with neuroprotective effectsAuthorZhang, J;Jiang, C;Shi, J;Liao, L;Zhang, L;Liu, J;Wang, Y;Lao, Y;Year2020JournalChemMedChemApplicationenzymePubMed ID: 32141184FoldedExpand
If you couldn"t find the specific citation, you can:
- Find All Citations
- Submit a CitationGet a Publication Reward
- Leave Us a Message
E.coli protein expression service
Mammalian transient protein expression service
Baculovirus-insect expression service
Stable cell line development service (CHO / HEK293)
品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
联络我们
