Sino Biological/CD36 Protein, Human, Recombinant (ECD, His Tag)/1/10752-H08H
商品编号：
10752-H08H
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
CD36 Protein, Human, Recombinant (ECD, His Tag): Product Information
Purity
> 88 % as determined by SDS-PAGE
Endotoxin
< 1.0="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the human CD36 (NP_001001547.1) extracellular domain (Gly 30-Asn 439) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
Accession#
NP_001001547.1
Expressed Host
HEK293 Cells
Species
Human
Predicted N Terminal
Gly30
Molecule Mass
The secreted recombinant human CD36 comprises 421 amino acids with a predicted molecular mass of 48.1 kDa. As a result of glycosylation, the apparent molecular mass of rh CD36 is approximately 62.6 kDa in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CD36 Protein, Human, Recombinant (ECD, His Tag): Images
CD36 Protein, Human, Recombinant (ECD, His Tag): Synonyms
BDPLT10 Protein, Human; CHDS7 Protein, Human; FAT Protein, Human; GP3B Protein, Human; GP4 Protein, Human; GPIV Protein, Human; PASIV Protein, Human; SCARB3 Protein, Human
CD36 Background Information
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 36 (CD36), also known as FAT, SCARB3, GP88, glycoprotein IV (gpIV) and glycoprotein IIIb (gpIIIb), is a member of the CD system as well as the class B scavenger receptor family of cell surface proteins. CD36 can be found on the surface of many cell types in vertebrate animals and it consists of 472 amino acids and is extensively glycosylated. It is an integral membrane protein primarily serving as receptors for thrombospondin and collagen and by the erythrocytes infected with the human malaria parasite. The role of CD36 as a cell surface receptor has been extended to that of a signal transduction molecule.
Full Name
CD36 molecule (thrombospondin receptor)
Research Areas
- Cancer Drug Targets
References
- Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
- Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
- Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
- Greenwalt RH, et al. (1992) Membrane glycoprotein in CD36: a review of its roles in adherence, signal transduction, and transfusion medicine. The journal of the American society of hematology. 80 (5): 1105-15.
Mouse CD36 Proteins
- CD36 Protein, Mouse, Recombinant (His & hFc Tag)50422-M03H
- CD36 Protein, Mouse, Recombinant (His Tag)50422-M08H
Rat CD36 Proteins
- CD36 Protein, Rat, Recombinant (His Tag)80263-R08H
- CD36 Protein, Rat, Recombinant (hFc Tag)80263-R02H
Rhesus CD36 Proteins
- CD36 Protein, Rhesus, Recombinant (hFc Tag)90184-C02H
- Probing the cytoadherence of malaria infected red blood cells under flowAuthorXu, X;Efremov, AK;Li, A;Lai, L;Dao, M;Lim, CT;Cao, J;Year2013JournalPLoS ONEApplicationadhesion experimentsPubMed ID: 23724092FoldedExpand
- Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinityAuthorTondera, C;Laube, M;Pietzsch, J;Year2016JournalAmino AcidsApplicationSPRPubMed ID: 27734162FoldedExpand
- Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicityAuthorBennett, NK;Chmielowski, R;Abdelhamid, DS;Faig, JJ;Francis, N;Baum, J;Pang, ZP;Uhrich, KE;Moghe, PV;Year2016JournalBiomaterialsApplicationbinding (pull-down)FoldedExpand
- All three human scavenger receptor class B proteins can bind and transport all three macular xanthophyll carotenoids.AuthorShyam, R;Vachali, P;Gorusupudi, A;Nelson, K;Bernstein, PS;Year2017JournalArch. Biochem. Biophys.PubMed ID: 28947101FoldedExpand
- Single molecule and multiple bond characterization of catch bond associated cytoadhesion in malariaAuthorLim, YB;Thingna, J;Cao, J;Lim, CT;Year2017JournalSci RepPubMed ID: 28646215FoldedExpand
- Analysis of exported proteins and parasite-induced host cell rigidity changes during the Plasmodium falciparum intraerythrocxytic life cycleAuthorSchibler, B;Year2018JournalThesisApplicationbindingFoldedExpand
- Fatty acid-induced CD36 expression via O-GlcNAcylation drives gastric cancer metastasisAuthorJiang, M;Wu, N;Xu, B;Chu, Y;Li, X;Su, S;Chen, D;Li, W;Shi, Y;Gao, X;Zhang, H;Zhang, Z;Du, W;Nie, Y;Liang, J;Fan, D;Year2019JournalTheranosticsApplicationsubstratePubMed ID: 31410220FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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