Sino Biological/MCP-1/CCL2 Protein, Human, Recombinant (His Tag)/1/10134-H08Y
商品编号：
10134-H08Y
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MCP-1/CCL2 Protein, Human, Recombinant (His Tag): Product Information
Purity
> 95 % as determined by SDS-PAGE.
Endotoxin
Please contact us for more information.
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the human CCL2 (NP_002973.1) (Gln24-Thr99) was expressed with a polyhistidine tag at the C-terminus.
Accession#
NP_002973.1
Expressed Host
Yeast
Species
Human
Predicted N Terminal
Gln 24
Molecule Mass
The recombinant human CCL2 consists 86 amino acids and predicts a molecular mass of 10.1 kDa.
Formulation
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
MCP-1/CCL2 Protein, Human, Recombinant (His Tag): Images
MCP-1/CCL2 Protein, Human, Recombinant (His Tag): Synonyms
GDCF-2 Protein, Human; HC11 Protein, Human; HSMCR30 Protein, Human; MCAF Protein, Human; MCP-1 Protein, Human; MCP1 Protein, Human; SCYA2 Protein, Human; SMC-CF Protein, Human
MCP-1/CCL2 Background Information
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.
- Cancer Immunotherapy
- Immune Checkpoint
- Immunotherapy
- Targeted Therapy
Full Name
chemokine (C-C motif) ligand 2
Research Areas
- Neuroinflammation
Related Pathways
IL17 signaling pathway
References
- Vásquez-Loarte T, Trubnykova M, Guio H. Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model. BMC Genetics. 2015;16:128.
Mouse MCP-1/CCL2 Proteins
- MCP-1/CCL2 Protein, Mouse, Recombinant (His Tag)50368-M08B
- MCP-1/CCL2 Protein, Mouse, Recombinant (His Tag), Biotinylated50368-M08B-B
- Inflammatory human umbilical cord-derived mesenchymal stem cells promote stem cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent MannerAuthorLuo, X;Huang, S;He, N;Liu, C;Chen, Y;Liu, Y;Mi, X;Li, N;Year2018JournalBioMed Research InternationalPubMed ID: 29670904FoldedExpand
- CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancerAuthorXu, W;Wei, Q;Han, M;Zhou, B;Wang, H;Zhang, J;Wang, Q;Sun, J;Feng, L;Wang, S;Ye, Y;Wang, X;Zhou, J;Jin, H;Year2018JournalInt. J. Biol. Sci.Applicationcell-basedPubMed ID: 29989092FoldedExpand
- Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor MicroenvironmentAuthorHou, PP;Luo, LJ;Chen, HZ;Chen, QT;Bian, XL;Wu, SF;Zhou, JX;Zhao, WX;Liu, JM;Wang, XM;Zhang, ZY;Yao, LM;Chen, Q;Zhou, D;Wu, Q;Year2020JournalMol. CellPubMed ID: 32470318FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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