Sino Biological/CD3D & CD3E Heterodimer Protein, Human, Recombinant (ECD)/1/CT026-H0323H
商品编号：
CT026-H0323H
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
CD3D & CD3E Heterodimer Protein, Human, Recombinant (ECD): Product Information
Purity
> 90 % as determined by SDS-PAGE
Endotoxin
< 1.0="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
Measured by its ability to bind OKT3-mIgG2a (Cat: 10977-M001) in a functional ELISA.
Protein Construction
A DNA sequence encoding the extracellular domain (Met1-Ala105) of human CD3D (P04234-1) was fused with the C-terminal his-tagged Fc region of human IgG1 at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Asp126) of human CD3E (P07766-1) was fused with the C-terminal flag-tagged Fc region of human IgG1 at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the human CD3D/CD3E heterodimer was purified.
Accession#
P04234-1 & P07766-1
Expressed Host
HEK293 Cells
Species
Human
Predicted N Terminal
Phe 22 & Asp 23
Molecule Mass
The recombinant heterodimer of human CD3D/CD3E consists of 687 (334+353) amino acids and predicts a molecular mass of 77.5 (37.7+39.8) kDa. It migrates as an approximately 44-54 KDa band in SDS-PAGE under reducing conditions due to glycosylation.
Formulation
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CD3D & CD3E Heterodimer Protein, Human, Recombinant (ECD): Images
CD3D & CD3E Heterodimer Protein, Human, Recombinant (ECD): Synonyms
CD3-DELTA Protein, Human; IMD19 Protein, Human; T3D Protein, Human
CD3D & CD3E Heterodimer Background Information
Full Name
CD3d molecule, delta (CD3-TCR complex)
Human CD3D & CD3E Heterodimer Proteins
- CD3D & CD3E Heterodimer Protein, Human, Recombinant (ECD, Flag & His Tag)CT038-H2508H
- CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His Tag), BiotinylatedCT038-H2508H-B
Mouse CD3D & CD3E Heterodimer Proteins
- CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Flag & His Tag)CT033-M2508H
- CD3D & CD3E Heterodimer Protein, Mouse, RecombinantCT025-M2303H
Cynomolgus CD3D & CD3E Heterodimer Proteins
- CD3D & CD3E Heterodimer Protein, Cynomolgus, RecombinantCT032-C0323H
- Novel multispecific heterodimeric antibody format allowing modular assembly of variable domain fragmentsAuthorEgan, TJ;Diem, D;Weldon, R;Neumann, T;Meyer, S;Urech, DM;Year2016JournalMAbsApplicationSPRPubMed ID: 27786600FoldedExpand
- Mabfilin and Fabfilin - New antibody-scaffold fusion formats for multispecific targeting conceptsAuthorKahl, M;Settele, F;Knick, P;Haupts, U;Bosse-Doenecke, E;Year2018JournalProtein Expr. Purif.ApplicationSPRPubMed ID: 29704557FoldedExpand
- A novel bispecific antibody targeting CD3 and prolactin receptor (PRLR) against PRLR-expression breast cancerAuthorZhou, Y;Zong, H;Han, L;Xie, Y;Jiang, H;Gilly, J;Zhang, B;Lu, H;Chen, J;Sun, R;Pan, Z;Zhu, J;Year2020JournalJ. Exp. Clin. Cancer Res.PubMed ID: 32398042FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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