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商品详细Sino Biological/FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag)/1/CT009-H08H
Sino Biological/FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag)/1/CT009-H08H
Sino Biological/FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag)/1/CT009-H08H
商品编号: CT009-H08H
品牌: sinobiological
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag): Product Information

Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 1.0="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
1. Measured by its ability to bind human IgG1 (Cat: 10702-HNAC) in a functional ELISA.2. Labeled biotin to FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag) by a certain molar ratio; Using the Octet RED System, the affinity constant (Kd) of FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag) bound to Conbercept was 0.1 μM.
Protein Construction
A DNA sequence encoding the extracellular domain (Met1-Ser297) of human FCGRT (P55899-1) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human B2M (P61770-1) (Met1-Met119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT / B2M heterodimer was purified.
Accession#
P55899-1 & P61770-1
Expressed Host
HEK293 Cells
Species
Human
Predicted N Terminal
Ala 24 & Ile 21
Molecule Mass
The recombinant heterodimer of human FCGRT/B2M comprises 384 (285+99) amino acids and has a calculated molecular mass of 43.5 (31.8+11.7) kDa. The apparent molecular mass of human FCGRT/B2M heterodimer is approximately 35 & 12 kDa respectively in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag): Images

Human FCGRT & B2M Protein 12984
Human FCGRT & B2M Heterodimer Protein 29974
Labeled biotin to FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag) by a certain molar ratio;Using the Octet RED System, the affinity constant (Kd) of FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag), Biotinylated (Cat. CT009-H08H-B) bound to Conbercept was 0.1 μM.
Human FCGRT & B2M Heterodimer Protein 24512
Human FCGRT & B2M Heterodimer Protein 24513

FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag): Synonyms

alpha-chain Protein, Human; FCRN Protein, Human

FCGRT & B2M Heterodimer Background Information

Full Name
Fc fragment of IgG, receptor, transporter, alpha
Research Areas
  • Fc Receptors

Human FCGRT & B2M Heterodimer Proteins

  • FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & AVI Tag)CT071-H27H
  • FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag), BiotinylatedCT009-H08H-B
  • FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & AVI Tag), BiotinylatedCT071-H27H-B

Mouse FCGRT & B2M Heterodimer Proteins

  • FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His & AVI Tag), BiotinylatedCT083-M27H-B
  • FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His Tag), BiotinylatedCT029-M08H-B
  • FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His Tag)CT029-M08H

Rat FCGRT & B2M Heterodimer Proteins

  • FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His Tag), BiotinylatedCT030-R08H-B
  • FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His Tag)CT030-R08H

Cynomolgus FCGRT & B2M Heterodimer Proteins

  • FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His Tag), BiotinylatedCT031-C08H-B
  • FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His & AVI Tag), BiotinylatedCT084-C27H-B
  • FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His Tag)CT031-C08H
  • Bispecific igg antibodies as t cell engagers
    Author
    ABH Bakker, PF Van Loo…
    Year
    2013
    Journal
    US 20140120096 A1
    FoldedExpand
  • Heterogeneous IgG interacts with FcRn and its transport across gastrointestinal barrier
    Author
    Pang, G;Qiao, D;Chen, Q;Hu, Z;Xie, J;
    Year
    2014
    Journal
    Food and Agricultural Immunology
    Application
    binding
    FoldedExpand
  • Distribution of FcRn Across Species and Tissues
    Author
    Latvala, S;Jacobsen, B;Otteneder, MB;Herrmann, A;Kronenberg, S;
    Year
    2017
    Journal
    J. Histochem. Cytochem.
    Application
    IHC
    PubMed ID: 28402755FoldedExpand
  • Towards a combinatorial approach for the prediction of immunoglobulin G half-life and clearance
    Author
    Goulet, DR;Watson, MJ;Tam, SH;Zwolak, A;Chiu, ML;Atkins, WM;Nath, A;
    Year
    2018
    Journal
    Drug Metab. Dispos.
    Application
    Octet
    FoldedExpand
  • The neonatal Fc receptor is a pan-echovirus receptor
    Author
    Morosky, S;Evans, A;Lemon, K;Schmus, S;Bakkenist, C;Coyne, C;
    Year
    2018
    Journal
    bioRxiv
    Application
    pull down
    FoldedExpand
  • Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms
    Author
    Wada, R;Matsui, M;Kawasaki, N;
    Year
    2018
    Journal
    MAbs
    Application
    SPR
    PubMed ID: 30466347FoldedExpand

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品牌介绍
北京义翘神州科技股份有限公司(Sino Biological Inc.)是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司,主要业务包括重组蛋白、抗体、基因和培养基等产品,以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种,其中重组蛋白约 6,000 种,包括超过 3,800 种人源细胞表达重组蛋白产品,能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求;公司还能提供约 12,000 种抗体,其中单克隆抗体数量约 4,600 种,能够覆盖生命科学研究的多个领域,为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司,已成为生物试剂行业国内领先的科技公司之一。