Sino Biological/Galectin 3/LGALS3 Protein, Human, Recombinant, Low Endotoxin/1/10289-HNAE-E
商品编号：
10289-HNAE-E
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Galectin 3/LGALS3 Protein, Human, Recombinant, Low Endotoxin: Product Information
Purity
> 97 % as determined by SDS-PAGE
Endotoxin
< 0.005="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 3-15 μg/ml.
Protein Construction
A DNA sequence encoding the human Galectin3 (P17931) (Met 1-Ile 250) was expressed and purified.
Accession#
P17931
Expressed Host
E. coli
Species
Human
Predicted N Terminal
Met 1
Molecule Mass
The recombinant human Galectin3 consisting of 250 amino acids and has a calculated molecular mass of 26.1 kDa. It migrates as an approximately 30 kDa band in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Galectin 3/LGALS3 Protein, Human, Recombinant, Low Endotoxin: Images
Galectin 3/LGALS3 Protein, Human, Recombinant, Low Endotoxin: Synonyms
CBP35 Protein, Human; GAL3 Protein, Human; GALBP Protein, Human; GALIG Protein, Human; L31 Protein, Human; LGALS2 Protein, Human; MAC2 Protein, Human
Galectin 3/LGALS3 Background Information
LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
Full Name
lectin, galactoside-binding, soluble, 3
References
- Dumic J, et al. (2006) Galectin-3: an open-ended story. Biochim Biophys Acta. 1760(4): 616-35.
- Sharma UC, et al. (2004) Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 110(19): 3121-8.
- Yan YP, et al. (2009) Galectin-3 mediates post-ischemic tissue remodeling. Brain Res. 1288: 116-24.
Human Galectin 3/LGALS3 Proteins
- Galectin 3/LGALS3 Protein, Human, Recombinant (His Tag)10289-H08H1
- Galectin 3/LGALS3 Protein, Human, Recombinant (His Tag)10289-H08H
- A crucial role of anti‐RPLP0 and anti‐galectin‐3 antibodies in the development of skin lesions in systemic lupus erythematosusAuthorZ Shi, G Tan, Z Meng, M Yu, K Li, J Yin…Year2014JournalArthritis & RheumatologyPubMed ID: 25307291FoldedExpand
- Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunctionAuthorSteinhorn, B;Sorrentino, A;Badole, S;Bogdanova, Y;Belousov, V;Michel, T;Year2018JournalNat CommunApplicationWB (control)PubMed ID: 30279532FoldedExpand
If you couldn"t find the specific citation, you can:
- Find All Citations
- Submit a CitationGet a Publication Reward
- Leave Us a Message
E.coli protein expression service
Mammalian transient protein expression service
Baculovirus-insect expression service
Stable cell line development service (CHO / HEK293)
品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
联络我们
