Sino Biological/银屑病/S100A7蛋白，人，重组/1/11141-HNAE
商品编号：
11141-HNAE
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Psoriasin/S100A7 Protein, Human, Recombinant: Product Information
Purity
> 98 % as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the native human S100A7 (NP_002954.2) (Met 1-Gln 101) was expressed.
Accession#
NP_002954.2
Expressed Host
E. coli
Species
Human
Predicted N Terminal
Met
Molecule Mass
The recombinant human S100A7 consisting of 101 amino acids and migrates as an 11.6 kDa band in SDS-PAGE under reducing conditions as predicted.
Formulation
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Psoriasin/S100A7 Protein, Human, Recombinant: Images
Psoriasin/S100A7 Protein, Human, Recombinant: Synonyms
PSOR1 Protein, Human; S100A7c Protein, Human
Psoriasin/S100A7 Background Information
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.
Full Name
S100 calcium binding protein A7
Research Areas
- Calcium-binding Proteins and Related Molecules
References
- Miyasaki,KT. et al., 1993, J. Dent. Res. 72: 517-23.
- Watson,PH. et al., 1998, Int J Biochem Cell Biol30(5):567-71.
- Emberley,ED. et al., 2004, Breast Cancer Res6(4): 153-9.
- Ohuchida,K.et al., 2006, Clin Cancer Res12(18):5417-22.
- Kouno,T. et al., 2008, J Pept Sci. 14(10):1129-38.
- León,R. et al., 2009, Biochemistry. 48(44):10591-600.
- Human S100A7 Induces Mature Interleukin1α Expression by RAGE-p38 MAPK-Calpain1 Pathway in PsoriasisAuthorLei, H;Li, X;Jing, B;Xu, H;Wu, Y;Year2017JournalPLoS ONEApplicationcell-basedPubMed ID: 28060905FoldedExpand
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E.coli protein expression service
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Stable cell line development service (CHO / HEK293)
品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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