Sino Biological/SerpinB8 Protein, Mouse, Recombinant (His Tag)/1/50215-M08B
商品编号：
50215-M08B
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
SerpinB8 Protein, Mouse, Recombinant (His Tag): Product Information
Purity
> 94 % as determined by SDS-PAGE
Endotoxin
< 1.0="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the mouse SERPINB8 (NP_035589.1) (Met 1-Pro 374) was expressed,with a C-terminal polyhistidine tag.
Accession#
NP_035589.1
Expressed Host
Baculovirus-Insect Cells
Species
Mouse
Predicted N Terminal
Ala 24
Molecule Mass
The recombinant mouse SERPINB8 consists of 385 amino acids and has a calculated molecular mass of 43.6 kDa as estimated in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
SerpinB8 Protein, Mouse, Recombinant (His Tag): Images
SerpinB8 Protein, Mouse, Recombinant (His Tag): Synonyms
CAP-2 Protein, Mouse; CAP2 Protein, Mouse; NK10 Protein, Mouse; ovalbumin Protein, Mouse; Spi8 Protein, Mouse
SerpinB8 Background Information
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal neuroendocrine tissues, strongest SerpinB8 expression was detected in islets of Langerhans of the pancreas. Moderate SerpinB8 expression was observed in neuroendocrine cells of the thyroid, adrenal cortex, colon, and pituitary gland. In the pancreas, SerpinB8 is specifically expressed by insulin-producing beta cells, and can be used as an additional diagnostic immunohistochemical marker. Mouse SerpinB8 distribution alters during kidney regeneration, possibly to control a prohormone convertase involved in inflammation or tissue repair.
Full Name
serpin peptidase inhibitor, clade B (ovalbumin), member 8
References
- Sumi,Y. et al., 1989, J. Biochem. 106: 703-7.
- Rawlings,N.D. et al., 2004, Biochem J. 378: 705-16.
- Gillard,A. et al., 2006, Am J Nephrol. 26(1): 34-42.
- Filleur,S. et al., 2009, J Cell Biochem. 106 (5): 769-75.
- deKoning, P.J. et al., 2009, Pancreas. 38(4): 461-7.
- Protease-inhibitor interaction predictions: Lessons on the complexity of protein-protein interactionsAuthorFortelny, N;Butler, GS;Overall, CM;Pavlidis, P;Year2017JournalMol. Cell ProteomicsApplicationProtein–protein interaction (PPI) networks of proteases and inhibitorsPubMed ID: 28385878FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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