Sino Biological/Peroxiredoxin 2蛋白，人，重组（His标签）/1/11255-H07B
商品编号：
11255-H07B
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Peroxiredoxin 2 Protein, Human, Recombinant (His Tag): Product Information
Purity
> 92 % as determined by SDS-PAGE
Endotoxin
< 1.0="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
Measured by its ability to reduce H2O2.The specific activity is >300 pmoles/min/μg.
Protein Construction
A DNA sequence encoding the human PRDX2 (P32119) (Met 1-Asn 198) was expressed, with a polyhistidine tag at the N-terminus.
Accession#
P32119
Expressed Host
Baculovirus-Insect Cells
Species
Human
Predicted N Terminal
Met
Molecule Mass
The recombinant human PRDX2 consists of 217 amino acids and predicts a molecular mass of 24 kDa. It migrates as an approximately 27 kDa band in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glyPlease contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Peroxiredoxin 2 Protein, Human, Recombinant (His Tag): Images
Peroxiredoxin 2 Protein, Human, Recombinant (His Tag): Synonyms
HEL-S-2a Protein, Human; NKEF-B Protein, Human; NKEFB Protein, Human; PRP Protein, Human; PRX2 Protein, Human; PRXII Protein, Human; PTX1 Protein, Human; TDPX1 Protein, Human; TPX1 Protein, Human; TSA Protein, Human
Peroxiredoxin 2 Background Information
Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein that belongs to the ahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains one thioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups (PRDX1，PRDX2, PRDX3, PRDX4, PRDX5, PRDX6) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.
Full Name
peroxiredoxin 2
References
- Cha M.-K., et al., 1995, Biochem. Biophys. Res. Commun. 217:900-7.
- Noh,D.Y. et al., 2001, Anticancer Res. 21(3B): 2085-90.
- Chevallet M., et al., 2003, J. Biol. Chem. 278:37146-53.
- Schremmer,B. et al., 2007, Subcell Biochem. 44:317-44.
- Gauci S., et al., 2009, Anal. Chem. 81:4493-501.
Mouse Peroxiredoxin 2 Proteins
- Peroxiredoxin 2 Protein, Mouse, Recombinant (His Tag)51862-M07B
- Serum proteomic-based analysis identifying autoantibodies against PRDX2 and PRDX3 as potential diagnostic biomarkers in nasopharyngeal carcinomaAuthorLin, LH;Xu, YW;Huang, LS;Hong, CQ;Zhai, TT;Liao, LD;Lin, WJ;Xu, LY;Zhang, K;Li, EM;Peng, YH;Year2017JournalClin ProteomicsApplicationELISAPubMed ID: 28184180FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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