Sino Biological/FABP5蛋白，人，重组/1/12581-HNAE
商品编号：
12581-HNAE
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
FABP5 Protein, Human, Recombinant: Product Information
Purity
> 92 % as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the human FABP5 (Q01469) (Met 1-Glu 135) was expressed and purified.
Accession#
Q01469
Expressed Host
E. coli
Species
Human
Predicted N Terminal
Met 1
Molecule Mass
The recombinant human FABP5 consisting of 135 amino acids and has a calculated molecular mass of 15.2 kDa as estimated in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile 50mM Tris, pH 8.0Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
FABP5 Protein, Human, Recombinant: Images
FABP5 Protein, Human, Recombinant: Synonyms
E-FABP Protein, Human; EFABP Protein, Human; KFABP Protein, Human; PA-FABP Protein, Human; PAFABP Protein, Human
FABP5 Background Information
Fatty acid-binding protein, alsoknown as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5,is a cytoplasm protein which Belongs to thecalycin superfamily andFatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs )are postulated to serve as lipid shuttles that solubilize hydrophobic fattyacids and deliver them to appropriate intracellular sites. E-FABP / FABP5 ispredominantly expressed in keratinocytes and is overexpressed in the activelyproliferating tissue characteristic of psoriasis and wound healing. E-FABP /FABP5 exhibits an important role in binding free fatty acids, as well asregulating lipid metabolism and transport. E-FABP / FABP5 has high specificityfor fatty acids. It has highest affinity for C18 chain length. Decreasing thechain length or introducing double bonds reduces the affinity of FABP5. E-FABP/ FABP5 may be involved in keratinocyte differentiation.
Full Name
fatty acid binding protein 5 (psoriasis-associated)
References
- HohoffC., et al., 1999, Biochemistry 38:12229-39
- Gutierrez-GonzalezL.H.,et al., 2002, Biochem. J. 364:725-37.
- Ogawa,E.et al., 2011, J Invest Dermatol. 131(3):604-12.
- Ma,X.et al.,2010, Mol Biol Rep. 37(8):4003-11.
- Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetesAuthorBurak, MF;Inouye, KE;White, A;Lee, A;Tuncman, G;Calay, ES;Sekiya, M;Tirosh, A;Eguchi, K;Birrane, G;Lightwood, D;Howells, L;Odede, G;Hailu, H;West, S;Garlish, R;Neale, H;Doyle, C;Moore, A;Hotamisligil, GS;Year2015JournalSci Transl MedPubMed ID: 26702093FoldedExpand
- Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr ResidueAuthorChen, W;Dong, J;Plate, L;Mortenson, DE;Brighty, GJ;Li, S;Liu, Y;Galmozzi, A;Lee, PS;Hulce, JJ;Cravatt, BF;Saez, E;Powers, ET;Wilson, IA;Sharpless, KB;Kelly, JW;Year2016JournalJ. Am. Chem. Soc.Applicationpositive controlPubMed ID: 27191344FoldedExpand
- Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunityAuthorSmole, U;Gour, N;Phelan, J;Hofer, G;Köhler, C;Kratzer, B;Tauber, PA;Xiao, X;Yao, N;Dvorak, J;Caraballo, L;Puerta, L;Rosskopf, S;Chakir, J;Malle, E;Lane, AP;Pickl, WF;Lajoie, S;Wills-Karp, M;Year2020JournalNat. Immunol.ApplicationimmunityPubMed ID: 32572240FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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