Sino Biological/Peroxiredoxin 1 Protein, Mouse, Recombinant (His Tag)/1/50552-M08E
商品编号：
50552-M08E
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Peroxiredoxin 1 Protein, Mouse, Recombinant (His Tag): Product Information
Purity
> 85 % as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the mouse PRDX1 (P35700) (Met 1-Lys 199) was expressed, with a C-terminal polyhistidine tag.
Accession#
P35700
Expressed Host
E. coli
Species
Mouse
Predicted N Terminal
Met 1
Molecule Mass
The recombinant mouse PRDX1 comprises 209 amino acids and has a calculated molecular mass of 23.5 kDa. The recombinant protein migrates as an approximately 27 kDa band in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, 10% glycerol, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Peroxiredoxin 1 Protein, Mouse, Recombinant (His Tag): Images
Peroxiredoxin 1 Protein, Mouse, Recombinant (His Tag): Synonyms
MSP23 Protein, Mouse; NkefA Protein, Mouse; OSF-3 Protein, Mouse; OSF3 Protein, Mouse; PAG Protein, Mouse; Paga Protein, Mouse; PrdxI Protein, Mouse; prx1 Protein, Mouse; PrxI Protein, Mouse; Tdpx2 Protein, Mouse; TDX2 Protein, Mouse; TPxA Protein, Mouse
Peroxiredoxin 1 Background Information
Peroxiredoxin-1, also known as Thioredoxin peroxidase 2, Natural killer cell-enhancing factor A, PRDX1, and PAGA, is a member of the ahpC/TSA family. Peroxiredoxin-1 is constitutively expressed in most human cells. It is induced to higher levels upon serum stimulation in untransformed and transformed cells. Peroxiredoxins (PRDXs) are a family of antioxidant enzymes that are also known as scavengers of peroxide in mammalian cells. The overexpression of Peroxiredoxin-1, which is one of the peroxiredoxins that is a ubiquitously expressed protein, was related to a poor prognosis in several types of human cancers. Peroxiredoxin-1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-1 Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The reduced Peroxiredoxin-1 expression is an important factor in esophageal squamous cancer progression and could serve as a useful prognostic marker.
Full Name
peroxiredoxin 1
References
- Neumann, CA. et al., 2003,Nature424(6948): 561-5
- Gisin, J. et al., 2005,J Clin Pathol. 58(11): 1229-31.
- Hoshino, I. et al., 2007, Oncol Rep. 18(4): 867-71.
- Cao, J. et al., 2009, EMBO J. 28(10): 1505-17.
Human Peroxiredoxin 1 Proteins
- Peroxiredoxin 1 Protein, Human, Recombinant (His Tag)11194-H08E
- Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in MacrophagesAuthorZhao, LX;Du, JR;Zhou, HJ;Liu, DL;Gu, MX;Long, FY;Year2016JournalPLoS ONEApplicationcell-basedPubMed ID: 27716839FoldedExpand
- Peroxiredoxin 1-mediated activation of TLR4/NF-B pathway contributes to neuroinflammatory injury in intracerebral hemorrhageAuthorLiu, DL;Zhao, LX;Zhang, S;Du, JR;Year2016JournalInternational ImmunopharmacologyApplicationcell-basedFoldedExpand
- Neuroprotective Effect of Phthalide Derivative CD21 against Ischemic Brain Injury:Involvement of MSR1 Mediated DAMP peroxiredoxin1 Clearance and TLR4 Signaling InhibitionAuthorZou, X;Yang, XJ;Gan, YM;Liu, DL;Chen, C;Duan, W;Du, JR;Year2020JournalJ Neuroimmune PharmacolApplicationFACSPubMed ID: 32291602FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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