华生物/Ephrin B2蛋白，小鼠，重组（hFc-Tag）/1/50598-M02H
商品编号：
50598-M02H
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Ephrin B2 Protein, Mouse, Recombinant (hFc Tag): Product Information
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 1.0="" eu="" per="" μg="" of="" the="" protein="" as="" determined="" by="" the="" lal="">
Activity
Measured by its binding ability in a functional ELISA. Immobilized mouse EphB4 at 2 μg/ml (100 μl/well) can bind mouse EphrinB2 Fc with a linear range of 0.2-25 ng/ml.
Protein Construction
A DNA sequence encoding the mouse EFNB2 (NP_034241.2) extracellular domain (Met 1-Ala 232) was expressed with the fused Fc region of human IgG1 at the C-terminus.
Accession#
NP_034241.2
Expressed Host
HEK293 Cells
Species
Mouse
Predicted N Terminal
Arg 29
Molecule Mass
The recombinant mouse EFNB2 comprises 445 amino acids and has a predicted molecular mass of 49 kDa.
Formulation
Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Ephrin B2 Protein, Mouse, Recombinant (hFc Tag): Images
Ephrin B2 Protein, Mouse, Recombinant (hFc Tag): Synonyms
ELF-2 Protein, Mouse; Epl5 Protein, Mouse; Eplg5 Protein, Mouse; Htk-L Protein, Mouse; LERK-5 Protein, Mouse; Lerk5 Protein, Mouse; NLERK-1 Protein, Mouse
Ephrin B2 Background Information
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing arterial and venous vessels at their junctions. The transmembrane-associated ephrin ligands and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Eph receptors and ephrins are divided into two subclasses, A and B, based on binding specificities. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. EphrinB2 expression progressively extends from the arterial endothelium to surrounding smooth muscle cells and to pericytes, suggesting that ephrin-B2 may play an important role during formation of the arterial muscle wall.
Full Name
ephrin-B2
References
- Wang HU, et al. (1998) Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 93(5): 741-53.
- Gale NW, et al. (2001) Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev Biol. 230(2): 151-60.
- Shin D, et al. (2001) Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev Biol. 230(2): 139-50.
Human Ephrin B2 Proteins
- Ephrin B2 Protein, Human, Recombinant (His Tag)10881-H08H
- Ephrin B2 Protein, Human, Recombinant (His & hFc Tag)10881-H03H
- Ephrin B2 Protein, Human, Recombinant10881-HCCH
Mouse Ephrin B2 Proteins
- Ephrin B2 Protein, Mouse, Recombinant (His Tag)50598-M08H
Rat Ephrin B2 Proteins
- Ephrin B2 Protein, Rat, Recombinant (His Tag)80107-R08H
- Ephrin B2 Protein, Rat, Recombinant (hFc Tag)80107-R02H
Canine Ephrin B2 Proteins
- Ephrin B2 Protein, Canine, Recombinant (hFc Tag)70073-D02H
- Ephrin B2 Protein, Canine, Recombinant (His Tag)70073-D08H
- Direct inhibition of cell surface ephrin-B2 by recombinant ephrin-B2/FCAuthorXiaodong, H;Zhen, H;Min, S;Zhiming, C;Hongyan, J;Chong, Z;Xuefeng, T;Guohua, J;Year2013JournalBiochem. Biophys. Res. Commun.ApplicationAssay for rapid ERK activityPubMed ID: 24076390FoldedExpand
- Eph/ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizerAuthorZhang, J;Jiang, Z;Liu, X;Meng, A;Year2016JournalDevelopmentApplicationbindingPubMed ID: 27287807FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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