Sino Biological/Influenza A Virus Hemagglutinin / HA Antibody, Rabbit MAb/1/86001-RM01
商品编号：
86001-RM01
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Influenza A Virus Hemagglutinin / HA Antibody, Rabbit MAb General Information
Product name
Influenza A Virus Hemagglutinin / HA Antibody, Rabbit MAb
Validated applications
WB,ELISA
Application notes
IHC, FCM, IF, IP et al. applications haven"t been validated.(Antibody"s applications haven"t been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.)
Specificity
Influenza Hemagglutinin/HAHas cross-reactivity in ELISA withH1N1 (A/Beijing/22808/2009) HAH1N1 (A/Brevig Mission/1/1918) HAH1N1 (A/Brisbane/59/2007) HAH1N1 (A/California/04/2009) HAH1N1 (A/California/07/2009) HAH1N1 (A/England/195/2009) HAH1N1 (A/New Caledonia/20/1999) HAH1N1 (A/New York/18/2009) HAH1N1 (A/Ohio/07/2009) HAH1N1 (A/Ohio/UR06-0091/2007) HAH1N1 (A/Puerto Rico/8/1934) HAH1N1 (A/Solomon Islands/3/2006) HAH1N1 (A/Texas/05/2009) HAH1N1 (A/WSN/1933) HAH1N2 (A/swine/Guangxi/13/2006) HAH1N3 (A/duck/NZL/160/1976) HAH2N2 (A/Canada/720/2005) HAH2N2 (A/Japan/305/1957) HAH3N2 (A/Aichi/2/1968) HAH3N2 (A/Brisbane/10/2007) HAH3N2 (A/Perth/16/2009) HAH3N2 (A/Wisconsin/67/X-161/2005) HAH3N2 (A/Wyoming/03/2003) HAH4N4 (A/mallard duck/Alberta/299/1977) HAH4N6 (A/mallard/Ohio/657/2002) HAH4N6 (A/Swine/Ontario/01911-1/99) HAH4N8 (A/chicken/Alabama/1/1975) HAH5N1 (A/Anhui/1/2005) HAH5N1 (A/Anhui/1/2005) HA2 Sub-unitH5N1 (A/bar-headed goose/Qinghai/14/2008) HAH5N1 (A/barnswallow/HongKong/D10-1161/2010) HA1 SubunitH5N1 (A/Cambodia/R0405050/2007) HAH5N1 (A/Cambodia/S1211394/2008) HAH5N1 (A/chicken/India/NIV33487/2006) HAH5N1 (A/Common magpie/Hong Kong/2256/2006) HAH5N1 (A/duck/Hunan/795/2002) HAH5N1 (A/Egypt/2321-NAMRU3/2007) HAH5N1 (A/Egypt/N05056/2009) HAH5N1 (A/goose/Guiyang/337/2006) HAH5N1 (A/Hong kong/213/03) HAH5N1 (A/Hong Kong/483/97) HAH5N1 (A/Hubei/2011) HAH5N1 (A/Indonesia/5/2005) HAH5N1 (A/Japanese white-eye/Hong Kong/1038/2006) HAH5N1 (A/turkey/Turkey/1/2005) HAH5N1 (A/Viet Nam/1203/2004) HAH5N1 (A/Vietnam/1194/2004) HAH5N1 (A/whooper swan/Mongolia/244/2005) HAH5N1 (A/Xinjiang/1/2006) HAH5N2 (A/American green-winged teal/California/HKWF609/07) HAH5N3 (A/duck/Hokkaido/167/2007) HAH5N8 (A/duck/NY/191255-59/2002) HAH6N1 (A/northern shoveler/California/HKWF115/2007) HAH6N4 (A/chicken/HongKong/17/77) HAH7N7 (A/chicken/Netherlands/1/03) HAH7N7 (A/Netherlands/219/03) HAH7N8 (A/mallard/Netherlands/33/2006) HAH7N9 (A/Anhui/1/2013) HAH7N9 (A/Hangzhou/1/2013) HAH7N9 (A/Hangzhou/3/2013) HAH7N9 (A/Pigeon/Shanghai/S1069/2013) HAH7N9 (A/Shanghai/1/2013) HAH7N9 (A/Shanghai/2/2013) HAH7N9 (A/Shanghai/4664T/2013) HAH7N9 (A/Zhejiang/1/2013) HAH8N4 (A/pintail duck/Alberta/114/1979) HAH9N2 (A/Chicken/Hong Kong/G9/97) HAH9N2 (A/Guinea fowl/Hong Kong/WF10/99) HAH9N2 (A/Hong Kong/1073/99) HAH9N2 (A/Hong Kong/35820/2009) HAH10N3 (A/duck/Hong Kong/786/1979) HAH10N3 (A/mallard/Minnesota/Sg-00194/2007) HAH10N9 (A/duck/HongKong/562/1979) HAH11N2 (A/duck/Yangzhou/906/2002) HAH11N9 (A/mallard/Alberta/294/1977) HAH12N1 (A/mallard duck/Alberta/342/1983) HAH12N5 (A/green-winged teal/ALB/199/1991) HAH13N8 (A/black-headed gull/Netherlands/1/00) HAH15N8 (A/duck/AUS/341/1983) HAH16N3 (A/black-headed gull/Sweden/5/99) HANo cross-reactivity in ELISA withH1N1 (A/Brevig Mission/1/1918) HAH1N1 (A/California/04/2009) HA1 Sub-unit,Influenza B (B/Florida/4/2006) HA
Immunogen
Recombinant H1N1 HA protein
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Influenza A virus H1N1 Hemagglutinin extracellular domain.
Source
Monoclonal Rabbit IgG Clone #2
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Influenza A Virus Hemagglutinin / HA Antibody, Rabbit MAb Validated Applications
| Application | Dilution |
|---|---|
| WB | his antibody can be used at 1:500-1:1000 with the appropriate secondary reagents to detect H1N1 HA in WB. |
| ELISA | 1:1000-1:2000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Hemagglutinin/HA Background Information
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells" sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.
Full Name
Harvey rat sarcoma viral oncogene homolog
References
- White JM, Hoffman LR, Arevalo JH, et al. Attachment and entry of influenza virus into host cells. Pivotal roles of hemagglutinin. In Chiu W, Burnett RM, Garcea RL. Structural Biology of Viruses.1997
- Suzuki Y.Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses. Biol. Pharm. Bull. 2005.
- Senne DA, Panigrahy B, Kawaoka Y, et al. Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential. Avian Dis. 1996
- Donald J. Benton,Influenza hemagglutinin membrane anchor,PNAS,2018
- Influenza A virus Utilizes a Suboptimal Kozak Sequence to Fine-tune Virus Replication and Host ResponseAuthorWang, J;Peng, Y;Zhao, L;Cao, M;Hung, T;Deng, T;Year2014JournalJ. Gen. Virol.PubMed ID: 25519170FoldedExpand
- New insights into the non-conserved non-coding region of the subtype-determinant HA and NA segments of influenza A virusesAuthorZhao, L;Peng, Y;Zhou, K;Cao, M;Wang, J;Wang, X;Jiang, T;Deng, T;Year2014JournalJ. Virol.PubMed ID: 25056889FoldedExpand
- Synthesis and anti-influenza virus activity of 4-oxo- or thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-onesAuthorJang, YJ;Achary, R;Lee, HW;Lee, HJ;Lee, CK;Han, SB;Jung, YS;Kang, NS;Kim, P;Kim, M;Year2014JournalAntiviral Res.ApplicationWBPubMed ID: 24794525FoldedExpand
- Protective neutralizing influenza antibody response in the absence of T follicular helper cellsAuthorMiyauchi, K;Sugimoto-Ishige, A;Harada, Y;Adachi, Y;Usami, Y;Kaji, T;Inoue, K;Hasegawa, H;Watanabe, T;Hijikata, A;Fukuyama, S;Maemura, T;Okada-Hatakeyama, M;Ohara, O;Kawaoka, Y;Takahashi, Y;Takemori, T;Kubo, M;Year2016JournalNat. Immunol.ApplicationELISAPubMed ID:27798619FoldedExpand
- The dual roles of the HA segment-specific noncoding nucleotides in the extended duplex region of the influenza A virus RNA promoterAuthorWang, J;Li, J;Zhao, L;Cao, M;Deng, T;Year2016JournalJ. Virol.ApplicationWBPubMed ID: 27795444FoldedExpand
- In Vitro and In Vivo Antiviral Activity of Nylidrin by Targeting the Hemagglutinin 2-Mediated Membrane Fusion of Influenza A VirusAuthorJang, Y;Shin, JS;Lee, JY;Shin, H;Kim, SJ;Kim, M;Year2020JournalVirusesPubMed ID: 32466302FoldedExpand
If you couldn"t find the specific citation, you can:
- Find All Citations
- Submit a CitationGet a Publication Reward
- Leave Us a Message
Recombinant Antibody Production Service
High-throughput Recombinant Antibody Production
Large-scale Antibody Production
Antibody Development Service
Rabbit MAb Production Service
Mouse MAb Production Service
Rabbit PAb Production Service
Phospho-Specific Antibody
Anti-Idiotype Antibody
Fast Antibody Development Service
Mouse MAb
Rabbit PAb
More Antibody Production Service
Hybridoma Antibody Production
Chimeric Antibody
Antibody Fragment
Bispecific Antibody
We also have Immunoassay Service. Click to see more.
品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
联络我们
