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当前位置: 首页 > 产品中心 > juhewu > Sino Biological/Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal/1/10289-R078
商品详细Sino Biological/Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal/1/10289-R078
Sino Biological/Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal/1/10289-R078
Sino Biological/Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal/1/10289-R078
商品编号: 10289-R078
品牌: sinobiological
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal General Information

Product name
Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal
Validated applications
WB,IP
Species reactivity
Reacts with: Human
Specificity
Human Galectin 3/LGALS3
Immunogen
Recombinant Human Galectin-3 / LGALS3 protein (Catalog#10289-HNAE)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human Galectin-3 / LGALS3 (rh Galectin-3 / LGALS3; Catalog#10289-HNAE; P17931; Met1-Ile250).
Source
Monoclonal Rabbit IgG Clone #078
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal Validated Applications

ApplicationDilution
WB1:500-1:2000
IP 1-4 μL/mg of lysate
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal Images

Human LGALS3 Western blot (WB) 13164

Anti-Galectin3 rabbit monoclonal antibody at 1:500 dilution

Lane A: Hela Whole Cell Lysate

Lane B: SW480 Whole Cell Lysate

Lane C: A431 Whole Cell Lysate

Lane D: MCF7 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:26 kDa

Observed band size:30 kDa

Human DDR1/MCK10/CD167 Immunoprecipitation(IP) 8012

Galectin3 was immunoprecipitated using:

Lane A:0.5 mg Hela Whole Cell Lysate

Lane B:0.5 mg MCF-7 Whole Cell Lysate

Lane C:0.5 mg A431 Whole Cell Lysate

2 µL anti-Galectin3 rabbit monoclonal antibody and 15 μl of50 %Protein G agarose.

Primary antibody:

Anti-Galectin3 rabbit monoclonal antibody,at 1:500 dilution

Secondary antibody:

Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution

Developed using the odssey technique.

Performed under reducing conditions.

Predicted band size: 30 kDa

Observed band size: 30 kDa

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal: Synonyms

Anti-CBP35 Antibody; Anti-GAL3 Antibody; Anti-GALBP Antibody; Anti-GALIG Antibody; Anti-L31 Antibody; Anti-LGALS2 Antibody; Anti-MAC2 Antibody

Galectin 3/LGALS3 Background Information

LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
Full Name
lectin, galactoside-binding, soluble, 3
References
  • Dumic J, et al. (2006) Galectin-3: an open-ended story. Biochim Biophys Acta. 1760(4): 616-35.
  • Sharma UC, et al. (2004) Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 110(19): 3121-8.
  • Yan YP, et al. (2009) Galectin-3 mediates post-ischemic tissue remodeling. Brain Res. 1288: 116-24.
  • Anti-Galectin 3/LGALS3 Antibody
    【Rabbit】【Polyclonal】【WB,IP】
    203092-T36
  • Anti-Galectin 3/LGALS3 Antibody
    【Rabbit】【Polyclonal】【WB,IP】
    10289-RP02
  • Anti-Galectin 3/LGALS3 Antibody
    【Rabbit】【Monoclonal】【IHC-P】
    10289-R102
  • Anti-Galectin 3/LGALS3 Antibody
    【Mouse】【Monoclonal】【WB,ELISA,IP】
    10289-MM01
  • Anti-Galectin 3/LGALS3 Antibody
    【Rabbit】【Monoclonal】【WB,ELISA,FCM,ICC/IF,IP】
    10289-R024
  • Anti-Galectin 3/LGALS3 Antibody
    【Rabbit】【Monoclonal】【ELISA,ELISA(Det)】
    10289-R179
  • Anti-Galectin 3/LGALS3 Antibody
    【Mouse】【Monoclonal】【ELISA(Cap)】
    10289-MM05
  • Chemogenetic Approaches to Studying Cardiovascular Redox Signaling in Vivo
    Author
    Steinhorn, B;
    Year
    2019
    Journal
    Thesis
    Application
    WB
    PubMed ID: 31298558FoldedExpand

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品牌介绍
北京义翘神州科技股份有限公司(Sino Biological Inc.)是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司,主要业务包括重组蛋白、抗体、基因和培养基等产品,以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种,其中重组蛋白约 6,000 种,包括超过 3,800 种人源细胞表达重组蛋白产品,能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求;公司还能提供约 12,000 种抗体,其中单克隆抗体数量约 4,600 种,能够覆盖生命科学研究的多个领域,为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司,已成为生物试剂行业国内领先的科技公司之一。