Sino Biological/Anti-TLR9 Antibody, Rabbit Polyclonal/1/102040-T08
商品编号：
102040-T08
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Anti-TLR9 Antibody, Rabbit Polyclonal General Information
Product name
Anti-TLR9 Antibody, Rabbit Polyclonal
Validated applications
IHC-P
Species reactivity
Reacts with: Mouse
Specificity
Mouse TLR9
Immunogen
A synthetic peptide corresponding to the C-terminus of the Mouse TLR9
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse TLR9, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-TLR9 Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| IHC-P | 1:500-1:2000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-TLR9 Antibody, Rabbit Polyclonal Images
-HD09DE0818-1ug-mouse-spleen-IHC-P.png)
Immunochemical staining of mouse TLR9 in mouse spleen with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
TLR9 Background Information
Toll-like receptors (TLRs) are important sensors that recognize pathogen-associated molecular patterns. Generally, TLR9 is known to recognize bacterial or viral DNA but not viral RNA and initiate an immune response. The significance of TLR9 in DENV-induced immune response is also confirmed in examination with the bone marrow-derived DCs prepared from Tlr9-knockout mice. As renal tubular epithelial TLR9 promotes cell injury and death whereas TLR9 signaling in other cell types may promote cytoprotective effects. TLR9 agonist delivered by inhalation is able to prime T cell responses against poorly immunogenic lung tumors and to complement the effects of PD-1 blockade.
Full Name
toll like receptor 9
Research Areas
- Neuroinflammation
- Cell-free DNA derived from cancer cells facilitates tumor malignancy through Toll-like receptor 9 signaling-triggered interleukin-8 secretion in colorectal cancerAuthorNiu, Z;Tang, W;Liu, T;Xu, P;Zhu, D;Ji, M;Huang, W;Ren, L;Wei, Y;Xu, J;Year2018JournalActa Biochim. Biophys. Sin. (Shanghai)ApplicationIHCPubMed ID: 30239551FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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