Sino Biological/Anti-c-Myc/MYC Antibody, Rabbit Polyclonal/1/100427-T32
商品编号：
100427-T32
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Anti-c-Myc/MYC Antibody, Rabbit Polyclonal General Information
Product name
Anti-c-Myc/MYC Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Human
Specificity
Human c-Myc/MYC
Immunogen
A synthetic peptide corresponding to the C-terminus of the human MYC
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the human MYC, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-c-Myc/MYC Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| WB | 1:500-1:1000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-c-Myc/MYC Antibody, Rabbit Polyclonal Images
-HB08SE1203-WB.png)
Anti-MYC rabbit polyclonal antibody at 1:500 dilution
Lane A: NIH-3T3 Whole Cell Lysate
Lysates/proteins at 30 μg per lane.
Secondary
Goat Anti-Rabbit IgG H&L (Dylight800)at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:48 kDa
Observed band size:48 kDa
(We are unsure as to the identity of these extra bands.)
Anti-c-Myc/MYC Antibody, Rabbit Polyclonal: Synonyms
Anti-bHLHe39 Antibody; Anti-c-Myc Antibody; Anti-MRTL Antibody; Anti-MYCC Antibody
c-Myc/MYC Background Information
MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis, and cellular transformation. MYC largely functions as a transcription factor that promotes the expression of numerous target genes to coordinate death, proliferation, and metabolism at the cellular, tissue, and organismal levels. MYC is one of the most important oncogenes in cancer. MYC overexpression can be achieved through a variety of mechanisms, including gene duplications, chromosomal translocations, or somatic mutations leading to increased MYC stability. It is widely expressed in the gall bladder, esophagus, and other tissues. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement.
Full Name
v-myc avian myelocytomatosis viral oncogene homolog
Research Areas
- Apoptosis Transcription Factors and Regulators
- Cancer Drug Targets
Related Pathways
EGFR Signaling Pathway
P38 MAPK Signaling Pathway
References
- Ding X, et al., 2009, PLoS One. 4(6): e5949.
- Ratsima H, et al., 2011, Proc Natl Acad Sci. 108(43): E914-23.
- Chiang YJ, et al., 2013, PLoS One. 8(4): e61761.
- Expression of Insulin-Like Growth Factor Binding Protein-5 (IGFBP5) Reverses Cisplatin-Resistance in Esophageal CarcinomaAuthorChan, D;Zhou, Y;Chui, CH;Lam, KH;Law, S;Chan, AS;Li, X;Lam, AK;Tang, JCO;Year2018JournalCellsApplicationIHCPubMed ID: 30241323FoldedExpand
- Discovery of [1,2,3]triazolo[4,5-d]pyrimidine derivatives as highly potent, selective, and cellularly active USP28 inhibitorsAuthorLiu, Z;Zhao, T;Li, Z;Sun, K;Fu, Y;Cheng, T;Guo, J;Yu, B;Shi, X;Liu, H;Year2019JournalActa Pharmaceutica Sinica BApplicationWBFoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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