Sino Biological/Anti-Psoriasin/S100A7 Antibody, Rabbit Polyclonal/1/11141-RP02
商品编号：
11141-RP02
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Anti-Psoriasin/S100A7 Antibody, Rabbit Polyclonal General Information
Product name
Anti-Psoriasin/S100A7 Antibody, Rabbit Polyclonal
Validated applications
WB,ELISA,IHC-P
Species reactivity
Reacts with: HumanNot React with: Mouse, Rat
Specificity
Human Psoriasin/S100A7
Immunogen
Recombinant Human S100A7 protein (Catalog#11141-HNAE)
Preparation
Produced in rabbits immunized with purified, recombinant Human S100A7 (rh S100A7; Catalog#11141-HNAE; NP_002954.2; Met 1-Gln 101). S100A7 specific IgG was purified by Human S100A7 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-Psoriasin/S100A7 Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| WB | 1:500-1:2000 |
| ELISA | 1:5000-1:10000 |
| IHC-P | 1:500-1:2000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-Psoriasin/S100A7 Antibody, Rabbit Polyclonal Images
-1ug-tonsil.png)
Immunochemical staining of human S100A7 in human tonsil with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to tonsil crypt and epithelium. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
-1ug-skin.png)
Immunochemical staining of human S100A7 in human skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to sweat gland. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
Anti-S100A7rabbit polyclonal antibody at 1:500 dilution
Lane A: A431 Whole Cell Lysate
Lysates/proteins at 30 μg per lane.
Secondary
Goat Anti-Rabbit IgG H&L (Dylight800)at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:11 kDa
Observed band size:15 kDa
Anti-Psoriasin/S100A7 Antibody, Rabbit Polyclonal: Synonyms
Anti-PSOR1 Antibody; Anti-S100A7c Antibody
Psoriasin/S100A7 Background Information
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.
Full Name
S100 calcium binding protein A7
Research Areas
- Calcium-binding Proteins and Related Molecules
References
- Miyasaki,KT. et al., 1993, J. Dent. Res. 72: 517-23.
- Watson,PH. et al., 1998, Int J Biochem Cell Biol30(5):567-71.
- Emberley,ED. et al., 2004, Breast Cancer Res6(4): 153-9.
- Ohuchida,K.et al., 2006, Clin Cancer Res12(18):5417-22.
- Kouno,T. et al., 2008, J Pept Sci. 14(10):1129-38.
- León,R. et al., 2009, Biochemistry. 48(44):10591-600.
- Human S100A7 Induces Mature Interleukin1α Expression by RAGE-p38 MAPK-Calpain1 Pathway in PsoriasisAuthorLei, H;Li, X;Jing, B;Xu, H;Wu, Y;Year2017JournalPLoS ONEApplicationELISAPubMed ID: 28060905FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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