Sino Biological/Anti-CD133/PROM1 Antibody, Rabbit Polyclonal/1/101955-T32
商品编号：
101955-T32
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Anti-CD133/PROM1 Antibody, Rabbit Polyclonal General Information
Product name
Anti-CD133/PROM1 Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Mouse
Specificity
Mouse CD133/PROM1
Immunogen
A synthetic peptide corresponding to the C-terminus of the Mouse PROM1
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse PROM1, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-CD133/PROM1 Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| WB | 1:500-1:2000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-CD133/PROM1 Antibody, Rabbit Polyclonal Images
-HD09NO0508-WB.png)
Anti-PROM1 rabbit polyclonal antibody at 1:500 dilution.
Lane A: Mouse Kidney Tissue lysate
Lysates/proteins at 30 μg per lane.
Secondary
Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:97 kDa
Observed band size:120 kDa
Anti-CD133/PROM1 Antibody, Rabbit Polyclonal: Synonyms
Anti-4932416E19Rik Antibody; Anti-AC133 Antibody; Anti-CD133 Antibody; Anti-Prom Antibody; Anti-Prom-1 Antibody; Anti-Proml1 Antibody
CD133/PROM1 Background Information
CD133, also known as PROM1 and Prominin 1, is a pentaspan transmembrane glycoprotein that belongs to the prominin family. It localizes to membrane protrusions and is often expressed on adult stem cells. CD133 is known to play a role in maintaining stem cell properties by suppressing differentiation. CD133 binds cholesterol in cholesterol-containing plasma membrane microdomains. It is proposed to play a role in apical plasma membrane organization of epithelial cells. CD133 is also involved in regulation of MAPK and Akt signaling pathways. Mutations in PROM1 gene have been shown to result in retinitis pigmentosa and Stargardt disease. PROM1 gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Expression of this gene is also associated with several types of cancer.
Full Name
prominin 1
Research Areas
- Hemangioblast Markers
References
- Corbeil D. et al., 2001, Biochem Biophys Res Commun. 285 (4): 939-44.
- Horn PA. et al., 1999, Blood. 93 (4): 1435-37.
- Sanai N. et al., 2005, N Engl J Med. 353 (8): 811-22.
- Effects of anoikis resistance on glioma cell proliferation and survivalAuthorGAO, L;YANG, F;LI, J;LONG, X;CHEN, B;Year2016JournalJournal of International Neurology and NeurosurgeryApplicationFACPubMed ID: 27473823FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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