Sino Biological/Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal/1/12656-RP02-免疫在线蚂蚁淘旗下平台

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商品详细Sino Biological/Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal/1/12656-RP02

Sino Biological/Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal/1/12656-RP02

商品编号： 12656-RP02

品牌： sinobiological

市场价： ¥0.00

美元价： 0.00

产地：美国(厂家直采)

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产品分类：聚合物

公司分类： juhewu

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal General Information

Product name

Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal

Validated applications

WB,ELISA,IHC-P,IP

Species reactivity

Reacts with: Human

Specificity

Human SOD2/Mn-SOD

Immunogen

Recombinant Human SOD2 protein (Catalog#12656-HNAE)

Preparation

Produced in rabbits immunized with purified, recombinant Human SOD2 (rh SOD2; Catalog#12656-HNAE; P04179-1; Lys 25-Lys 222). SOD2 specific IgG was purified by Human SOD2 affinity chromatography.

Source

Polyclonal Rabbit IgG

Purification

Protein A & Antigen Affinity

Formulation

0.2 μm filtered solution in PBS

Conjugate

Unconjugated

Form

Liquid

Shipping

This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal Validated Applications

Application	Dilution
WB	1:500-1:2000
ELISA	1:5000-1:10000
IHC-P	1:500-1:2000
IP	1-4 μL/mg of lysate

Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal Images

Human SOD2 Immunohistochemistry(IHC) 3566

Immunochemical staining of human SOD2 in human placenta with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Human SOD2 Immunohistochemistry(IHC) 3568

Immunochemical staining of human SOD2 in human kidney with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Human SOD2 Immunohistochemistry(IHC) 3571

Immunochemical staining of human SOD2 in human colon carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Anti-SOD2 rabbit polyclonal antibody at 1:500 dilution

Lane A: HelaWhole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800)at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:24 kDa

Observed band size:25 kDa

(We are unsure as to the identity of these extra bands.)

Human SOD2 Immunoprecipitation(IP) 23919

SOD2 was immunoprecipitated using:

Lane A:0.5 mg Hela Whole Cell Lysate

Lane B:0.5 mg HEPG2 Whole Cell Lysate

Lane C:0.5 mg 293TWhole Cell Lysate

4 µL anti-SOD2 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein A/G.

Primary antibody:

Anti-SOD2 rabbit polyclonal antibody,at 1:100 dilution

Secondary antibody:

Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution

Developed using the ECL technique.

Performed under reducing conditions.

Predicted band size: 24 kDa

Observed band size :24 kDa

Anti-SOD2/Mn-SOD Antibody, Rabbit Polyclonal: Synonyms

Anti-IPOB Antibody; Anti-MNSOD Antibody; Anti-MVCD6 Antibody

SOD2/Mn-SOD Background Information

Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. Mitochondrial superoxide dismutase [SOD; manganese SOD (MnSOD) or SOD2] neutralizes highly reactive superoxide radical (O^•-₂), the first member in the plethora of mitochondrial reactive oxygen species.

Full Name

superoxide dismutase 2, mitochondrial

References

Culotta VC, et al. (2006) Activation of superoxide dismutases: putting the metal to the pedal. Biochim Biophys Acta. 1763(7): 747-58.
Bag A, et al. (2008) Target sequence polymorphism of human manganese superoxide dismutase gene and its association with cancer risk: a review. Cancer Epidemiol Biomarkers Prev. 17(12): 3298-305.
Diehl C, et al. (2009) The basis of topical superoxide dismutase antipruritic activity. Acta Dermatovenerol Croat. 17(1): 25-39.
Ma X, et al. (2010) No association between SOD2 Val16Ala polymorphism and breast cancer susceptibility: a meta-analysis based on 9,710 cases and 11,041 controls. Breast Cancer Res Treat. 122(2): 509-14.

Anti-SOD2/Mn-SOD Antibody
【Rabbit】【Monoclonal】【WB,ELISA,IP】
12656-R001
Anti-SOD2/Mn-SOD Antibody
【Rabbit】【Polyclonal】【ELISA】
12656-RP01
Anti-SOD2/Mn-SOD Antibody
【Rabbit】【Monoclonal】【IHC-P】
12656-R012

The regulator of calcineurin 1 increases adenine nucleotide translocator 1 and leads to mitochondrial dysfunctions
Author
Jiang, H;Zhang, C;Tang, Y;Zhao, J;Wang, T;Liu, H;Sun, X;
Year
2016
Journal
J. Neurochem.
Application
WB
PubMed ID: 27861892FoldedExpand

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品牌介绍

北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。

公司介绍

品牌分类

Elisa试剂盒试剂蛋白质试剂抗体试剂 Gene Reagent

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