Sino Biological/Mouse TLR4 qPCR Primer Pair/1/MP200636
商品编号：
MP200636
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Mouse TLR4 qPCR Primer Pair: General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃.The suspended product is stable for six months from date of receipt when stored at -20℃.
***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI"s proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***
Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Mouse TLR4 qPCR Primer Pair: Synonyms
Lps qPCR Primer Pairs, Mouse; Ly87 qPCR Primer Pairs, Mouse; Ran/M1 qPCR Primer Pairs, Mouse; Rasl2-8 qPCR Primer Pairs, Mouse
TLR4 Background Information
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. TLR 4 has also been designated as CD284 (cluster of differentiation 284). It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. TLR4 Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It is also involved in LPS-independent inflammatory responses triggered by Ni(2+).
Full Name
toll-like receptor 4
Research Areas
- Neuroinflammation
Related Pathways
NF-kB (NFkB) Pathway
References
- Re, Fabio, et al. (2002) Monomeric recombinant MD-2 binds toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness. J Biol Chem. 277(26):23427-32.
- Shimazu, R, et al. (1999) MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4. J Exp Med. 189(11):1777-82.
- Blanco, A M, et al. (2005) Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. Journal of immunology. 175(10):6893-9.
TLR4 qPCR Primer Pairs, Human, Related Products
- TLR4 cDNA ORF Clone, Human, N-DYKDDDDK (Flag®) tagHG10146-NF
- TLR4 cDNA ORF Clone, Human, N-Myc tagHG10146-NM
- TLR4 cDNA ORF Clone, Human, N-HA tagHG10146-NY
- TLR4 cDNA ORF Clone, Human, C-His tagHG10146-CH
- TLR4 cDNA ORF Clone, Human, C-HA tagHG10146-CY
- TLR4 cDNA ORF Clone in Cloning Vector, HumanHG10146-M
- TLR4 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tagHG10146-ACGLN
- TLR4 cDNA ORF Clone, Human, C-OFPSpark® tagHG10146-ACR
- TLR4 cDNA ORF Clone, Human, C-Myc tagHG10146-CM
- TLR4 cDNA ORF Clone, Human, C-GFPSpark® tagHG10146-ACG
- TLR4 cDNA ORF Clone, Human, N-His tagHG10146-NH
- TLR4 cDNA ORF Clone, Human, untaggedHG10146-UT
- TLR4 cDNA ORF Clone, Human, C-DYKDDDDK (Flag®) tagHG10146-CF
TLR4 qPCR Primer Pairs, Mouse, Related Products
- TLR4 cDNA ORF Clone, Mouse, C-His tagMG50657-CH
- TLR4 cDNA ORF Clone in Cloning Vector, MouseMG50657-M
- TLR4 cDNA ORF Clone, Mouse, N-His tagMG50657-NH
- TLR4 cDNA ORF Clone, Mouse, C-Myc tagMG50657-CM
- TLR4 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tagMG50657-ACGLN
- TLR4 cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tagMG50657-CF
- TLR4 cDNA ORF Clone, Mouse, N-HA tagMG50657-NY
- TLR4 cDNA ORF Clone, Mouse, N-DYKDDDDK (Flag®) tagMG50657-NF
- TLR4 cDNA ORF Clone, Mouse, C-OFPSpark® tagMG50657-ACR
- TLR4 cDNA ORF Clone, Mouse, C-GFPSpark® tagMG50657-ACG
- TLR4 cDNA ORF Clone, Mouse, C-HA tagMG50657-CY
- TLR4 cDNA ORF Clone, Mouse, N-Myc tagMG50657-NM
- TLR4 cDNA ORF Clone, Mouse, untaggedMG50657-UT
TLR4 qPCR Primer Pairs, Rat, Related Products
- TLR4 cDNA ORF Clone, Rat, untaggedRG80389-UT
- TLR4 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tagRG80389-ACGLN
- TLR4 cDNA ORF Clone, Rat, C-GFPSpark® tagRG80389-ACG
- TLR4 cDNA ORF Clone in Cloning Vector, RatRG80389-G
- TLR4 cDNA ORF Clone, Rat, C-His tagRG80389-CH
- TLR4 cDNA ORF Clone, Rat, C-Myc tagRG80389-CM
- TLR4 cDNA ORF Clone, Rat, C-HA tagRG80389-CY
- TLR4 cDNA ORF Clone, Rat, C-DYKDDDDK (Flag®) tagRG80389-CF
- TLR4 cDNA ORF Clone, Rat, N-Myc tagRG80389-NM
- TLR4 cDNA ORF Clone, Rat, N-HA tagRG80389-NY
- TLR4 cDNA ORF Clone, Rat, C-OFPSpark® tagRG80389-ACR
- TLR4 cDNA ORF Clone, Rat, N-DYKDDDDK (Flag®) tagRG80389-NF
- TLR4 cDNA ORF Clone, Rat, N-His tagRG80389-NH
TLR4 qPCR Primer Pairs, Rhesus, Related Products
- TLR4 cDNA ORF Clone, Rhesus, N-His tagCG90258-NH
- TLR4 Lentiviral cDNA ORF Clone, Rhesus, C-GFPSpark® tagCG90258-ACGLN
- TLR4 cDNA ORF Clone, Rhesus, C-DYKDDDDK (Flag®) tagCG90258-CF
- TLR4 cDNA ORF Clone, Rhesus, C-OFPSpark® tagCG90258-ACR
- TLR4 cDNA ORF Clone, Rhesus, C-HA tagCG90258-CY
- TLR4 cDNA ORF Clone, Rhesus, N-Myc tagCG90258-NM
- TLR4 cDNA ORF Clone, Rhesus, C-GFPSpark® tagCG90258-ACG
- TLR4 cDNA ORF Clone, Rhesus, C-His tagCG90258-CH
- TLR4 cDNA ORF Clone in Cloning Vector, RhesusCG90258-G
- TLR4 cDNA ORF Clone, Rhesus, N-HA tagCG90258-NY
- TLR4 cDNA ORF Clone, Rhesus, N-DYKDDDDK (Flag®) tagCG90258-NF
- TLR4 cDNA ORF Clone, Rhesus, C-Myc tagCG90258-CM
- TLR4 cDNA ORF Clone, Rhesus, untaggedCG90258-UT
- Developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure of either parent enhances the risk of necrotizing enterocolitis in neonatal miceAuthorMokshagundam, S;Ding, T;Rumph, JT;Dallas, M;Stephens, VR;Osteen, KG;Bruner-Tran, KL;Year2020JournalBirth Defects ResApplicationqPCRPubMed ID: 32519502FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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