Sino Biological/SLPI cDNA ORF Clone, Human, C-GFPSpark® tag/1/HG10343-ACG
商品编号：
HG10343-ACG
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
SLPI cDNA ORF Clone, Human, C-GFPSpark® tag: General Information
Gene
Species
Human
NCBI Ref Seq
NM_003064.2
RefSeq ORF Size
1128 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human secretory leukocyte peptidase inhibitor with C terminal GFPSpark tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-C-GFPSpark®
Restriction Sites
KpnI + XbaI(6kb+1.13kb)
Tag Sequence
GFPSpark: GTGAGCAAGGGC……GAGCTGTACAAG
Sequencing Primers
T7( 5" TAATACGACTCACTATAGGG 3" )BGH( 5" TAGAAGGCACAGTCGAGG 3" )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
SLPI cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
SLPI cDNA ORF Clone, Human, C-GFPSpark® tag: Validated Images
SLPI cDNA ORF Clone, Human, C-GFPSpark® tag: Synonyms
ALK1 cDNA ORF Clone, Human; ALP cDNA ORF Clone, Human; BLPI cDNA ORF Clone, Human; HUSI cDNA ORF Clone, Human; HUSI-I cDNA ORF Clone, Human; MPI cDNA ORF Clone, Human; WAP4 cDNA ORF Clone, Human; WFDC4 cDNA ORF Clone, Human
SLPI Background Information
Secretory leukoprotease inhibitor (SLPI), also called antileukoprotease (ALP), is a 12-kDa, nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in protecting the mucosae from injury associated with inflammation. SLPI is locally produced by serous cells, including bronchial submucosal glands. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions. Elafin and SLPI are structurally related in that both have a fold with a four-disulfide core or whey acidic protein (WAP) domain responsible for inhibiting proteases. SLPI is a prominent innate immune protein of the respiratory tract, possessing serine protease inhibitor activity, antibacterial activity, and anti-inflammatory/immunomodulatory activity.
Full Name
secretory leukocyte peptidase inhibitor
Research Areas
- Serine Proteases and Regulators
References
- Moreau T, et al. (2008) Multifaceted roles of human elafin and secretory leukocyte proteinase inhibitor (SLPI), two serine protease inhibitors of the chelonianin family. Biochimie. 90(2): 284-95.
- Weldon S, et al. (2007) Innate host defense functions of secretory leucoprotease inhibitor. Exp Lung Res. 33(10): 485-91.
- Williams SE, et al. (2006) SLPI and elafin: one glove, many fingers. Clin Sci (Lond). 110(1): 21-35.
- Kikuchi T, et al. (1996) Regulation of secretory leukoprotease inhibitor gene expression. Nihon Rinsho. 54(2): 405-10.
SLPI cDNA ORF Clone, Human,Related Products
- SLPI cDNA ORF Clone, Human, untaggedHG10343-UT
- SLPI cDNA ORF Clone, Human, C-OFPSpark® tagHG10343-ACR
- SLPI cDNA ORF Clone, Human, C-Myc tagHG10343-CM
- SLPI cDNA ORF Clone, Human, N-Myc tagHG10343-NM
- SLPI cDNA ORF Clone in Cloning Vector, HumanHG10343-M
- SLPI cDNA ORF Clone, Human, C-HA tagHG10343-CY
- SLPI cDNA ORF Clone, Human, N-His tagHG10343-NH
- SLPI cDNA ORF Clone, Human, C-DYKDDDDK (Flag®) tagHG10343-CF
- SLPI cDNA ORF Clone, Human, C-His tagHG10343-CH
- SLPI cDNA ORF Clone, Human, N-HA tagHG10343-NY
- SLPI Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tagHG10343-ACGLN
- SLPI cDNA ORF Clone, Human, N-DYKDDDDK (Flag®) tagHG10343-NF
- Human SLPI qPCR Primer PairHP100381
- Endothelial-Cell-Derived Human Secretory Leukocyte Protease Inhibitor (SLPI) Protects Cardiomyocytes against Ischemia/Reperfusion InjuryAuthorKongpol, K;Nernpermpisooth, N;Prompunt, E;Kumphune, S;Year2019JournalBiomoleculesApplicationexpressionPubMed ID: 31683729FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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