Sino Biological/SUV39H1 cDNA ORF Clone, Human, C-OFPSpark® tag/1/HG11498-ACR
商品编号：
HG11498-ACR
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
SUV39H1 cDNA ORF Clone, Human, C-OFPSpark® tag: General Information
Gene
Species
Human
NCBI Ref Seq
NM_003173.3
RefSeq ORF Size
1926 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 1110C/T not causing the amino acid variation.
Description
Full length Clone DNA of Human suppressor of variegation 3-9 homolog 1 (Drosophila) with C terminal OFPSpark / RFP tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-C-OFPSpark®
Restriction Sites
KpnI + XbaI(6kb+1.93kb)
Tag Sequence
OFPSpark Tag: GATAGCACTGAG……CACCTGTTCCAG
Sequencing Primers
T7( 5" TAATACGACTCACTATAGGG 3" )BGH( 5" TAGAAGGCACAGTCGAGG 3" )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
SUV39H1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
SUV39H1 cDNA ORF Clone, Human, C-OFPSpark® tag: Validated Images
SUV39H1 cDNA ORF Clone, Human, C-OFPSpark® tag: Synonyms
H3-K9-HMTase1 cDNA ORF Clone, Human; KMT1A cDNA ORF Clone, Human; MG44 cDNA ORF Clone, Human; SUV39H cDNA ORF Clone, Human
SUV39H1 Background Information
SUV39H1, the histone methyltransferase (HMTase) of histone H3 lysine 9 trimethylation (H3K9me3), is a known transcriptional repressor of inflammatory genes. SUV39H1 as an oncogene in melanoma and underscore the role of chromatin factors in regulating tumorigenesis. The ability of mycobacteria to form biofilms, a survival strategy of the bacteria dependent upon cell-cell adhesion, was dramatically reduced in the presence of SUV39H1. Thus, this novel defense mechanism against mycobacteria represents a surrogate function of the epigenetic modulator, SUV39H1, and operates by interfering with their cell-cell adhesion ability. Overexpression of SUV39H1 may reduce renal inflammation and apoptosis via epigenetic modulation, thus plays a protective role in DN.
Full Name
suppressor of variegation 3-9 homolog 1 (Drosophila)
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SUV39H1 cDNA ORF Clone, Rat,Related Products
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- Clinical significance of LOXL4 expression and features of LOXL4-associated protein-protein interaction network in esophageal squamous cell carcinomaAuthorXie, W;Huang, P;Wu, B;Chen, S;Huang, Z;Wang, J;Sun, H;Wu, J;Xie, L;Cheng, Y;Xie, W;Xu, L;Chen, LQ;Li, E;Zou, H;Year2019JournalAmino AcidsPubMed ID: 30900087FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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