Sino Biological/MITF cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tag/1/MG57009-CF
商品编号：
MG57009-CF
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MITF cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tag: General Information
Gene
Species
Mouse
NCBI Ref Seq
NM_001178049.1
RefSeq ORF Size
1533 bp
Description
Full length Clone DNA of Mouse microphthalmia-associated transcription factor with C terminal Flag tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-C-FLAG
Tag Sequence
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
Sequencing Primers
T7( 5" TAATACGACTCACTATAGGG 3" )BGH( 5" TAGAAGGCACAGTCGAGG 3" )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.
More Information About MITF
Entrez Gene ID
17342
MITF cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tag: Synonyms
BCC2 cDNA ORF Clone, Mouse; Bhlhe32 cDNA ORF Clone, Mouse; bw cDNA ORF Clone, Mouse; Gsfbcc2 cDNA ORF Clone, Mouse; mi cDNA ORF Clone, Mouse; vit cDNA ORF Clone, Mouse; Vitiligo cDNA ORF Clone, Mouse; Wh cDNA ORF Clone, Mouse
MITF Background Information
Microphthalmia-associated transcription factor (MITF) is a member of the basic helix-loop-helix leucine zipper (bHLH-Zip) family and functions as the master regulator of the melanocytic lineage.MITF (Microphthalmia-associated transcription factor) is a lineage-specific transcription factor that plays a critical role in melanocyte homeostasis and whose deregulation has been shown to contribute to melanoma disease. Microphthalmia-associated transcription factor (MITF) is expressed in melanomas and has a critical role in melanocyte development and transformation. Because inhibition of MITF inhibits cell growth in melanoma, MITF is a potential therapeutic target molecule. Microphthalmia-associated transcription factor (MITF) regulates the transcription of its target genes by binding to their promoters. Microphthalmia-associated transcription factor (MITF) is a key regulator of differentiation of melanocytes and retinal pigment epithelial cells, but it also has functions in non-pigment cells.
Full Name
microphthalmia-associated transcription factor
Related Pathways
MAPK-Erk Pathway
MITF cDNA ORF Clone, Human,Related Products
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- Human MITF qPCR Primer PairHP101275
MITF cDNA ORF Clone, Mouse,Related Products
- MITF cDNA ORF Clone, Mouse, C-HA tagMG57009-CY
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- MITF cDNA ORF Clone in Cloning Vector, MouseMG57009-U
- MITF cDNA ORF Clone, Mouse, N-Myc tagMG57009-NM
- MITF cDNA ORF Clone, Mouse, N-GFPSpark® tagMG57009-ANG
- MITF cDNA ORF Clone, Mouse, N-OFPSpark® tagMG57009-ANR
- MITF cDNA ORF Clone, Mouse, N-His tagMG57009-NH
- MITF cDNA ORF Clone, Mouse, C-His tagMG57009-CH
- MITF cDNA ORF Clone, Mouse, N-HA tagMG57009-NY
- MITF cDNA ORF Clone, Mouse, untaggedMG57009-UT
- MITF Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tagMG57009-ACGLN
- MITF cDNA ORF Clone, Mouse, C-Myc tagMG57009-CM
- MITF cDNA ORF Clone, Mouse, C-GFPSpark® tagMG57009-ACG
- The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in MelanomaAuthorPhung, B;Cieśla, M;Sanna, A;Guzzi, N;Beneventi, G;Cao Thi Ngoc, P;Lauss, M;Cabrita, R;Cordero, E;Bosch, A;Rosengren, F;Häkkinen, J;Griewank, K;Paschen, A;Harbst, K;Olsson, H;Ingvar, C;Carneiro, A;Tsao, H;Schadendorf, D;Pietras, K;Bellodi, C;Jönsson, G;Year2019JournalCell RepApplicationexpressionPubMed ID: 31216476FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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