Sino Biological/HSD17B4 cDNA ORF Clone in Cloning Vector, Mouse/1/MG52990-G
商品编号：
MG52990-G
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
HSD17B4 cDNA ORF Clone in Cloning Vector, Mouse: General Information
Gene
Species
Mouse
NCBI Ref Seq
NM_008292.4
RefSeq ORF Size
2208 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Mouse hydroxysteroid (17-beta) dehydrogenase 4.
Plasmid
Vector
pGEM-T Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
HSD17B4 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
HSD17B4 cDNA ORF Clone in Cloning Vector, Mouse: Synonyms
17-beta-HSD cDNA ORF Clone, Mouse; 17[b]-HSD cDNA ORF Clone, Mouse; 4 cDNA ORF Clone, Mouse; DBP cDNA ORF Clone, Mouse; MFE-2 cDNA ORF Clone, Mouse; Mfp-2 cDNA ORF Clone, Mouse; MFP2 cDNA ORF Clone, Mouse; MPF-2 cDNA ORF Clone, Mouse; perMFE-2 cDNA ORF Clone, Mouse
HSD17B4 Background Information
HSD17B4 (Hydroxysteroid 17-Beta Dehydrogenase 4) is a Protein Coding gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. HSD17B4 is highly expressed in human liver cancer tissues, and it participates in liver cancer cell proliferation via suppressing estradiol (E2) activity. HSD17B4 was overexpressed in prostate and colon cancer tissues, knocking down HSD17B4 inhibited cancer cell proliferation, suggesting that HSD17B4 is a potential biomarker and drug target and that CLIFs are potential probes or therapeutic agents for these cancers. D-bifunctional protein deficiency, caused by recessive mutations in HSD17B4, is a severe, infantile-onset disorder of peroxisomal fatty acid oxidation.
Full Name
hydroxysteroid (17-beta) dehydrogenase 4
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- HSD17B4 cDNA ORF Clone, Mouse, N-His tagMG52990-NH
- HSD17B4 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tagMG52990-ACGLN
- HSD17B4 cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tagMG52990-CF
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- Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomesAuthorZhu, Z;Chen, J;Wang, G;Elsherbini, A;Zhong, L;Jiang, X;Qin, H;Tripathi, P;Zhi, W;Spassieva, SD;Morris, AJ;Bieberich, E;Year2019JournalBiochim Biophys Acta Mol Cell Biol LipidsApplicationtemplatePubMed ID: 31176039FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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