Sino Biological/NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-DYKDDDDK (Flag®) tag/1/HG16974-NF
商品编号：
HG16974-NF
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-DYKDDDDK (Flag®) tag: General Information
Gene
Species
Human
NCBI Ref Seq
NM_015965.6
RefSeq ORF Size
435 bp
Description
Full length Clone DNA of Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 with N terminal Flag tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-N-FLAG
Tag Sequence
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
Sequencing Primers
T7( 5" TAATACGACTCACTATAGGG 3" )BGH( 5" TAGAAGGCACAGTCGAGG 3" )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.
NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-DYKDDDDK (Flag®) tag: Synonyms
B16.6 cDNA ORF Clone, Human; CDA016 cDNA ORF Clone, Human; CGI-39 cDNA ORF Clone, Human; GRIM-19 cDNA ORF Clone, Human; GRIM19 cDNA ORF Clone, Human
NDUFA13/GRIM 19 Background Information
NDUFA13 (NADH: Ubiquinone Oxidoreductase Subunit A13) is a Protein Coding gene. NDUFA13 belongs to the complex I NDUFA13 subunit family. This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. NDUFA13 has a unique molecular structure, and its location is very close to the subunits of complex I of low electrochemical potential. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor and can function as a tumor suppressor. Diseases associated with NDUFA13 include Mitochondrial Complex I Deficiency, Nuclear Type 28 and Thyroid Carcinoma, Hurthle Cell. Among its related pathways are GABAergic synapse and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Full Name
NADH:ubiquinone oxidoreductase subunit A13
References
- Zhao D, et al. (2018) Retinoid interferon-induced mortality19 (grim19) inhibits proliferation and invasion in rheumatoid arthritis fibroblast-like synoviocytes. Biomed Pharmacother 98 719-725.
- Yang Y, et al. (2018) Expression of grim-19 in unexplained recurrent spontaneous abortion and possible pathogenesis. Mol Hum Reprod 24 (7): 366-374.
- Hu H, et al. (2017) Electron leak from ndufa13 within mitochondrial complex i attenuates ischemia-reperfusion injury via dimerized stat3. Proc Natl Acad Sci U S A 114 (45): 11908-11913.
NDUFA13/GRIM 19 cDNA ORF Clone, Human,Related Products
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, C-OFPSpark® tagHG16974-ACR
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, C-Myc tagHG16974-CM
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-OFPSpark® tagHG16974-ANR
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, C-GFPSpark® tagHG16974-ACG
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, C-His tagHG16974-CH
- NDUFA13/GRIM 19 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tagHG16974-ACGLN
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-His tagHG16974-NH
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-GFPSpark® tagHG16974-ANG
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, C-DYKDDDDK (Flag®) tagHG16974-CF
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-Myc tagHG16974-NM
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, untaggedHG16974-UT
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, C-HA tagHG16974-CY
- NDUFA13/GRIM 19 cDNA ORF Clone in Cloning Vector, HumanHG16974-U
- NDUFA13/GRIM 19 cDNA ORF Clone, Human, N-HA tagHG16974-NY
- Repression of GRIM19 expression potentiates cisplatin chemoresistance in advanced bladder cancer cells via disrupting ubiquitination-mediated Bcl-xL degradationAuthorNi, F;Yan, CY;Zhou, S;Hui, PY;Du, YH;Zheng, L;Yu, J;Hu, XJ;Zhang, ZG;Year2018JournalCancer Chemother. Pharmacol.ApplicationexpressionPubMed ID: 30032449FoldedExpand
If you couldn"t find the specific citation, you can:
- Find All Citations
- Submit a CitationGet a Publication Reward
- Leave Us a Message
品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
联络我们
