Sino Biological/Human SP1 qPCR Primer Pair/1/HP101560
商品编号：
HP101560
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Human SP1 qPCR Primer Pair: General Information
Target Details
Species:
Human
NCBI RefSeq:
NM_138473.2, NM_003109.1, NM_001251825.1
PCR Size:
166bp
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃.The suspended product is stable for six months from date of receipt when stored at -20℃.
***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI"s proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***
Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Human SP1 qPCR Primer Pair: Synonyms
TSFP1 qPCR Primer Pairs, Human
SP1 Background Information
Sp1 (specificity protein 1) belongs to the 26 member strong Sp/KLF family of transcription factors. Sp1 is a well-known member of a family of transcription factors that also includes Sp2, Sp3, and Sp4, which are implicated in an ample variety of essentially biological processes and have been proven important in cell growth, differentiation, apoptosis, and carcinogenesis. Sp1 activates the transcription of many cellular genes that contain putative CG-rich Sp-binding sites in their promoters. Sp1 also has a role in the DNA damage response; at low levels of DNA damage, Sp1 is phosphorylated by ATM and localizes to double-strand break sites where it facilitates DNA double-strand break repair. Depletion of Sp1 increases the sensitivity of cells to DNA damage, whereas overexpression of Sp1 can drive cells into apoptosis. In response to a variety of stimuli, Sp1 can be regulated through proteolytic cleavage by caspases and/or degradation.
Full Name
Sp1 transcription factor
References
- Vizcaíno C, et al. (2015) Sp1 transcription factor: A long-standing target in cancer chemotherapy. Pharmacol Ther 152 111-124.
- Torabi B, et al. (2018) Caspase cleavage of transcription factor sp1 enhances apoptosis. Apoptosis 23 (1): 65-78.
- O"Connor L, et al. (2016) The role of the ubiquitously expressed transcription factor sp1 in tissue-specific transcriptional regulation and in disease. Yale J Biol Med 89 (4): 513-525.
- Beishline K, et al. (2015) Sp1 and the "hallmarks of cancer". Febs j 282 (2): 224-258.
SP1 qPCR Primer Pairs, Human, Related Products
- SP1 cDNA ORF Clone, Human, N-GFPSpark® tagHG12024-ANG
- SP1 cDNA ORF Clone, Human, C-DYKDDDDK (Flag®) tagHG12024-CF
- SP1 cDNA ORF Clone, Human, C-OFPSpark® tagHG12024-ACR
- SP1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tagHG12024-ACGLN
- SP1 cDNA ORF Clone in Cloning Vector, HumanHG12024-G
- SP1 cDNA ORF Clone, Human, N-His tagHG12024-NH
- SP1 cDNA ORF Clone, Human, N-Myc tagHG12024-NM
- SP1 cDNA ORF Clone, Human, N-HA tagHG12024-NY
- SP1 cDNA ORF Clone, Human, N-DYKDDDDK (Flag®) tagHG12024-NF
- SP1 cDNA ORF Clone, Human, N-OFPSpark® tagHG12024-ANR
- SP1 cDNA ORF Clone, Human, C-His tagHG12024-CH
- SP1 cDNA ORF Clone, Human, C-Myc tagHG12024-CM
- SP1 cDNA ORF Clone, Human, C-GFPSpark® tagHG12024-ACG
- SP1 cDNA ORF Clone, Human, untaggedHG12024-UT
- SP1 cDNA ORF Clone, Human, C-HA tagHG12024-CY
- Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cellsAuthorJin, L;Miao, J;Liu, Y;Li, X;Jie, Y;Niu, Q;Han, X;Year2016JournalBiomed. Pharmacother.ApplicationPCRFoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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