Sino Biological/CD48 ELISA Kit, Human/1/KIT10797
商品编号：
KIT10797
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
CD48 ELISA Kit, Human: General Information
Product name
CD48 ELISA Kit, Human
Assay type
Solid Phase Sandwich ELISA (quantitative)
Conjugate
HRP
Sample type
Serum
Sensitivity
2.1 pg/mL
Assay range
9.38-600 pg/mL
Specificity
Recognizes both recombinant and natural Human CD48
Precision
| Intra-assay Precision | |||
|---|---|---|---|
| Sample | 1 | 2 | 3 |
| N | 20 | 20 | 20 |
| Mean(pg/mL) | 147.00 | 261.00 | 501.00 |
| SD | 4.59 | 5.61 | 21.54 |
| CV(%) | 3.1% | 2.1% | 4.3% |
| Inter-assay Precision | |||
| Sample | 1 | 2 | 3 |
| N | 20 | 20 | 20 |
| Mean(pg/mL) | 151.00 | 256.00 | 487.00 |
| SD | 11.41 | 17.55 | 46.85 |
| CV(%) | 7.5% | 6.8% | 9.6% |
Recovery
The recovery of Human CD48 spiked to different levels throughout the range of the assay in related matrices was evaluated.
| Sample |
|---|
| serum (n=3) |
| Average % Recovery |
| 107 |
| Range |
| 99 -115% |
| Sample |
| supernatant (n=3) |
| Average % Recovery |
| 103 |
| Range |
| 99 -107% |
Linearity
Serum
| Recovery of detected | |
|---|---|
| 1:1 | 94% |
| 1:2 | 100% |
| 1:4 | 106% |
| 1:8 | 112% |
Supernatant
| Recovery of detected | |
|---|---|
| 1:1 | 80% |
| 1:2 | 94% |
| 1:4 | 106% |
| 1:8 | 118% |
Materials provided
1. 96 well microplate coated with Capture Antibody2. Detection Antibody conjugated to HRP3. Standards4. Wash Buffer Concentrate5. Dilution Buffer Concentrate6. Color Reagent A7. Color Reagent B8. Stop Solution
Product overview
This CD48 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human CD48 protein in Serum . It contains recombinant Human CD48, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
Shipping
This ELISA Kit is shipped at ambient temperature.
Storage
Unopened Kit: Store at 2 - 8℃Opened/Reconstituted Reagents: Please refer to CoA
CD48 ELISA Kit, Human: Images
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
This assay recognizes both recombinant and natural Human CD48. The factors listed above were prepared at 50 ng/mL in dilution buffer and assayed for cross -reactivity. No cross-reactivity was observed.
CD48 ELISA Kit, Human: Synonyms
BCM1 ELISA Kit, Human; BLAST ELISA Kit, Human; Blast-1 ELISA Kit, Human; BLAST1 ELISA Kit, Human; hCD48 ELISA Kit, Human; mCD48 ELISA Kit, Human; MEM-102 ELISA Kit, Human; SLAMF2 ELISA Kit, Human
CD48 Background Information
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
- Cancer Immunotherapy
- Co-inhibitory Immune Checkpoint Targets
- Immune Checkpoint
- Immune Checkpoint Detection: Antibodies
- Immune Checkpoint Detection: ELISA Antibodies
- Immune Checkpoint Detection: FCM Antibodies
- Immune Checkpoint Detection: ICC Antibodies
- Immune Checkpoint Detection: IHC Antibodies
- Immune Checkpoint Detection: IP Antibodies
- Immune Checkpoint Detection: WB Antibodies
- Immune Checkpoint Proteins
- Immune Checkpoint Targets
- Immunotherapy
- Targeted Therapy
Full Name
CD48 molecule
Research Areas
- Cancer Drug Targets
References
- Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
- Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
- The Asthma-associated PER1-like domain-containing protein 1 (PERLD1) Haplotype Influences Soluble Glycosylphosphatidylinositol Anchor Protein (sGPI-AP) Levels in Serum and Immune Cell ProliferationAuthorSio, YY;Anantharaman, R;Lee, SQE;Matta, SA;Ng, YT;Chew, FT;Year2020JournalSci RepApplicationELISAPubMed ID: 31959860FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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