Sino Biological/IL-1β匹配ELISA抗体对集，人/1/SEK10139
商品编号：
SEK10139
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
IL-1 beta Matched ELISA Antibody Pair Set,Human General Information
Product name
IL-1 beta Matched ELISA Antibody Pair Set,Human
Assay type
Solid Phase Sandwich ELISA
Specificity
Quantitative determination of Human IL-1 beta
Assay range
78.13-5000 pg/mL
Materials provided
1. Capture Antibody 1 mg/mL of mouse anti-Human IL-1 beta / IL1B / IL-1F2 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 0.5 μg/mL in PBS before coating. (Catalog: # 10139-MM07)2. Detection Antibody 0.2 mg/mL of mouse anti-Human IL-1 beta / IL1B / IL-1F2 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.15 μg/mL in Dilution Buffer before use. (Catalog: # 10139-MM09)3. Standard Each vial contains 178 ng of recombinant Human IL-1 beta / IL1B / IL-1F2. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in Dilution Buffer, and a high standard of 5000 pg/mL is recommended.
Product overview
This IL-1 beta Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human IL-1 beta . It contains Human IL-1 beta capture antibody, Human IL-1 beta detector antibody (HRP)and a highly purifiedE. coli-expressedrecombinant Human IL-1 beta protein. This Pair Set is at affordable price for researchers.
Shipping
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
Storage
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
IL-1 beta Matched ELISA Antibody Pair Set,Human Images
IL-1 beta Matched ELISA Antibody Pair Set,Human: Synonyms
IL-1 Matched ELISA Antibody Pair Set, Human; IL-1 beta Matched ELISA Antibody Pair Set, Human; IL-1B Matched ELISA Antibody Pair Set, Human; IL1-BETA Matched ELISA Antibody Pair Set, Human; IL1F2 Matched ELISA Antibody Pair Set, Human
IL-1 beta Background Information
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
- Cancer Immunotherapy
- Immune Checkpoint
- Immunotherapy
- Targeted Therapy
Full Name
interleukin 1, beta
Research Areas
- Neuroinflammation
Related Pathways
IL1 signaling pathway
References
- Kim SH, et al. (2008) Association of -31TC and -511 CT polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis. 14:2109-16.
- Wang ZC, et al. (2002) T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun. 3(1): 38-42.
- Mattuzzi S, et al. (2007) Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol. 34(5): 997-1004.
- Rheumatoid arthritis-associated microRNA-155 targets SOCS1 and upregulates TNF-α and IL-1β in PBMCsAuthorLi, X;Tian, F;Wang, F;Year2013JournalInt J Mol SciPubMed ID: 24351865FoldedExpand
- LncRNA-MEG3 alleviates high glucose induced inflammation and apoptosis of retina epithelial cells via regulating miR-34a/SIRT1 axisAuthorTong, P;Peng, QH;Gu, LM;Xie, WW;Li, WJ;Year2018JournalExp. Mol. Pathol.ApplicationELISAPubMed ID: 30529346FoldedExpand
- Fatty acylCoA synthetase FadD13 regulates proinflammatory cytokine secretion dependent on the NF-κB signalling pathway by binding to eEF1A1AuthorWei, S;Wang, D;Li, H;Bi, L;Deng, J;Zhu, G;Zhang, J;Li, C;Li, M;Fang, Y;Zhang, G;Chen, J;Tao, S;Zhang, XE;Year2019JournalCell. Microbiol.ApplicationELISAPubMed ID: 31364251FoldedExpand
- AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB PathwayAuthorRen, J;Han, Y;Ren, T;Fang, H;Xu, X;Lun, Y;Jiang, H;Xin, S;Zhang, J;Year2019JournalJ. Atheroscler. Thromb.PubMed ID: 31462616FoldedExpand
- Combined Amelioration of Prebiotic Resveratrol and Probiotic Bifidobacteria on Obesity and Nonalcoholic Fatty Liver DiseaseAuthorHu, D;Yang, W;Mao, P;Cheng, M;Year2020JournalNutr CancerPubMed ID: 32436410FoldedExpand
- Rhein laden pH-responsive polymeric nanoparticles for treatment of osteoarthritisAuthorHu, B;Gao, F;Li, C;Zhang, B;An, M;Lu, M;Liu, Y;Liu, Y;Year2020JournalAMB ExpressApplicationELISAPubMed ID: 32865763FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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