Sino Biological/Her2/ERBB2 Matched ELISA Antibody Pair Set,Human/1/SEKA10004
商品编号：
SEKA10004
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Her2/ERBB2 Matched ELISA Antibody Pair Set,Human General Information
Product name
Her2/ERBB2 Matched ELISA Antibody Pair Set,Human
Assay type
Solid Phase Sandwich ELISA
Specificity
Quantitative determination of Human Her2/ERBB2
Assay range
24-1500 pg/mL
Materials provided
1. Capture Antibody 1 mg/mL of rabbit anti-Human HER2 / ErbB2 / CD340 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 1 μg/mL in PBS before coating. (Catalog: # 10004-R511)2. Detection Antibody 0.1 mg/mL of rabbit anti-Human HER2 / ErbB2 / CD340 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10004-R205)3. Standard Each vial contains 110 ng of recombinant Human HER2 / ErbB2 / CD340. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 1500 pg/mL is recommended.
Product overview
This Her2/ERBB2 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human Her2/ERBB2 . It contains Human Her2/ERBB2 capture antibody, Human Her2/ERBB2 detector antibody (HRP)and a highly purifiedHEK293-expressedrecombinant Human Her2/ERBB2 protein. This Pair Set is at affordable price for researchers.
Shipping
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
Storage
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
Her2/ERBB2 Matched ELISA Antibody Pair Set,Human Images
Her2/ERBB2 Matched ELISA Antibody Pair Set,Human: Synonyms
CD340 Matched ELISA Antibody Pair Set, Human; ENV Matched ELISA Antibody Pair Set, Human; ENVW Matched ELISA Antibody Pair Set, Human; ERVWE1 Matched ELISA Antibody Pair Set, Human; HER-2 Matched ELISA Antibody Pair Set, Human; HER-2/neu Matched ELISA Antibody Pair Set, Human; HER2 Matched ELISA Antibody Pair Set, Human; HERV-7q Matched ELISA Antibody Pair Set, Human; HERV-W-ENV Matched ELISA Antibody Pair Set, Human; HERV7Q Matched ELISA Antibody Pair Set, Human; HERVW Matched ELISA Antibody Pair Set, Human; HERVWENV Matched ELISA Antibody Pair Set, Human; MLN 19 Matched ELISA Antibody Pair Set, Human; MLN19 Matched ELISA Antibody Pair Set, Human; NEU Matched ELISA Antibody Pair Set, Human; NGL Matched ELISA Antibody Pair Set, Human; TKR1 Matched ELISA Antibody Pair Set, Human
Her2/ERBB2 Background Information
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
- Cancer Immunotherapy
- Immune Checkpoint
- Immunotherapy
- Targeted Therapy
Full Name
erb-b2 receptor tyrosine kinase 2
Research Areas
- Cancer Drug Targets
- Receptor Tyrosine Kinases (RTKs)
References
- Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.
- Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCCAuthorBattke, C;Ruiss, R;Welsch, U;Wimberger, P;Lang, S;Jochum, S;Zeidler, R;Year2011JournalCancer Immunol. Immunother.ApplicationAntibodies and ELISA assaysPubMed ID: 21293856FoldedExpand
- Disposable Amperometric Immunosensor for the Determination of Human P53 Protein in Cell Lysates Using Magnetic Micro-CarriersAuthorPedrero, M;Manuel de Villena, FJ;Muñoz-San Martín, C;Campuzano, S;Garranzo-Asensio, M;Barderas, R;Pingarrón, JM;Year2016JournalBiosensors (Basel)ApplicationELISAPubMed ID: 27879639FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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