Sino Biological/Anti-CYP2E1 Antibody, Rabbit Polyclonal/1/102050-T40
商品编号：
102050-T40
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Anti-CYP2E1 Antibody, Rabbit Polyclonal General Information
Product name
Anti-CYP2E1 Antibody, Rabbit Polyclonal
Validated applications
WB,IHC-P
Species reactivity
Reacts with: Human
Specificity
Human CYP2E1
Immunogen
A synthetic peptide corresponding to the center region of the Human CYP2E1 / Cytochrome P450 2E1
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human CYP2E1 / Cytochrome P450 2E1, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-CYP2E1 Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| WB | 1:500-1:1000 |
| IHC-P | 1:2500-1:10000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-CYP2E1 Antibody, Rabbit Polyclonal Images
-HD09DE0705-WB.png)
Anti-CYP2E1 rabbit polyclonal antibody at 1:500 dilution
Lane A: HepG2 Whole Cell Lysate
Lane B: HeLa Whole Cell Lysate
Lysates/proteins at 30 μg per lane.
Secondary
Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:57 kDa
Observed band size:70 kDa
-HD09DE0705-1ug-liver-IHC-P.png)
Immunochemical staining of human CYP2E1 in human liver with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).
-HD09DE0705-1ug-hepatoma-IHC-P.png)
Immunochemical staining of human CYP2E1 in human hepatoma with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).
Anti-CYP2E1 Antibody, Rabbit Polyclonal: Synonyms
Anti-CPE1 Antibody; Anti-CYP2E Antibody; Anti-P450-J Antibody; Anti-P450C2E Antibody
CYP2E1 Background Information
Cytochrome P450 2E1 (CYP2E1) is an important drug metabolizing enzyme for processing numerous xenobiotics in the liver, including acetaminophen and ethanol. CYP2E1 is an important mediator of RIPF development that functions by increasing cellular ER stress and ROS levels. CYP2E1 metabolizes an extensive array of pollutants, drugs, and other small molecules, often resulting in bioactivation to reactive metabolites. Increased CYP2E1 protein and activity levels can be the main cause of stress-mediated liver damage in diabetes. CYP2E1 gene encodes a drug-metabolizing enzyme that metabolizes mostly small, polar molecules, including toxic laboratory chemicals.
Full Name
cytochrome P450 family 2 subfamily E member 1
- Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicityAuthorKouam, A;Owona, B;Fifen, R;Njayou, F;Moundipa, P;Year2020JournalHeliyonApplicationWBFoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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