Sino Biological/Anti-EGR1 Antibody, Rabbit Polyclonal/1/100899-T32
商品编号：
100899-T32
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Anti-EGR1 Antibody, Rabbit Polyclonal General Information
Product name
Anti-EGR1 Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Human
Specificity
Human EGR1
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human EGR1
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human EGR1, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-EGR1 Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| WB | 1:500-1:2000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-EGR1 Antibody, Rabbit Polyclonal Images
-HD09AU1815-WB.png)
Anti-EGR1 rabbit polyclonal antibody at 1:500 dilution
Lane A: HeLa Whole Cell Lysate
Lane B: MDA-MB231 Whole Cell Lysate
Lysates/proteins at 30 μg per lane.
Secondary
Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:57 kDa
Observed band size:55 kDa
Anti-EGR1 Antibody, Rabbit Polyclonal: Synonyms
Anti-AT225 Antibody; Anti-G0S30 Antibody; Anti-KROX-24 Antibody; Anti-NGFI-A Antibody; Anti-TIS8 Antibody; Anti-ZIF-268 Antibody; Anti-ZNF225 Antibody
EGR1 Background Information
Early growth response 1 (EGR1) is an early response transcriptional regulator that can be rapidly induced by various environmental stimuli, the increase of EGR1 expression in epithelial cells is a common stress induced, cell type specific response upon host-bacteria interaction that is mediated by EGFR-ERK1/2 and beta1-integrin signaling. Early growth response 1 (Egr1) is a key transcription factor that mediates the action of estrogen (E2) to establish uterine receptivity for embryo implantation. Early growth response transcription factor 1 (EGR1) is expressed in the suprachiasmatic nucleus (SCN) after light stimulation, the circadian clock in the SCN is disturbed in mice deficient of EGR1. The transcription factor EGR1 (early growth response 1) is a member of a zinc finger transcription factor family which plays an essential role in cell growth and proliferation. EGR1 expression levels in human gliomas are decreased compared with normal brain tissues, however, the patients with low EGR1 expression level showed significantly enhanced patient survival in all glioma patients. EGR1 silencing inhibited proliferation and induced G1 phase arrest in glioma cells.
Full Name
early growth response 1
Related Pathways
B Cell Receptor Signaling Pathway
- CD9 Defines Acute Myeloid Leukemia Stem Cells and is Regulated by Alpha-2-MacroglobulinAuthorLiu, Y;Wang, G;Zhang, J;Chen, X;Xu, H;Heng, G;Chen, J;Zhao, Y;Li, J;Ni, Y;Zhang, Y;Liu, L;Shan, J;Qian, C;Year2020JournalResearch SquareApplicationWBFoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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