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商品详细Sino Biological/Anti-RND3 Antibody, Rabbit Polyclonal/1/101056-T32
Sino Biological/Anti-RND3 Antibody, Rabbit Polyclonal/1/101056-T32
Sino Biological/Anti-RND3 Antibody, Rabbit Polyclonal/1/101056-T32
商品编号: 101056-T32
品牌: sinobiological
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Anti-RND3 Antibody, Rabbit Polyclonal General Information

Product name
Anti-RND3 Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Human Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology)
Specificity
Human RND3
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human RND3
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human RND3, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-RND3 Antibody, Rabbit Polyclonal Validated Applications

ApplicationDilution
WB1:500-1:1000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-RND3 Antibody, Rabbit Polyclonal Images

Human RND3 Western blot (WB) 6553

Anti-RND3 rabbit polyclonal antibody at 1:500 dilution

Lane A: NCI-H460 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800)at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:27 kDa

Observed band size:30 kDa

Anti-RND3 Antibody, Rabbit Polyclonal: Synonyms

Anti-ARHE Antibody; Anti-memB Antibody; Anti-Rho8 Antibody; Anti-RhoE Antibody

RND3 Background Information

Forced expression of RND3 inhibited Snail1 activity, which in turn blocked glioblastoma cell migration and invasion in vitro in cell culture and in vivo in GBM xenograft mice. Activation of Notch signaling contributes to glioblastoma multiform (GBM) tumorigenesis. The downregulation of RND3 is responsible for the enhancement of Notch activity that promotes glioblastoma genesis.
Full Name
Rho family GTPase 3
    • Counteracting Genome Instability by p53-dependent Mintosis
      Author
      Liang, J;Niu, Z;Yu, X;Zhang, B;Wang, M;Ruan, B;Qin, H;
      Year
      2020
      Journal
      bioRxiv
      Application
      WB
      FoldedExpand

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    品牌介绍
    北京义翘神州科技股份有限公司(Sino Biological Inc.)是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司,主要业务包括重组蛋白、抗体、基因和培养基等产品,以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种,其中重组蛋白约 6,000 种,包括超过 3,800 种人源细胞表达重组蛋白产品,能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求;公司还能提供约 12,000 种抗体,其中单克隆抗体数量约 4,600 种,能够覆盖生命科学研究的多个领域,为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司,已成为生物试剂行业国内领先的科技公司之一。