中华生物/抗GAPDH抗体，兔多克隆/1/100242-T08
商品编号：
100242-T08
品牌：
sinobiological
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Anti-GAPDH Antibody, Rabbit Polyclonal General Information
Product name
Anti-GAPDH Antibody, Rabbit Polyclonal
Validated applications
IHC-P
Species reactivity
Reacts with: Human
Specificity
Human GAPDH
Immunogen
A synthetic peptide corresponding to the center regionof the human GAPDH
Preparation
Produced in rabbits immunized with A synthetic peptide corresponding to the center regionof the human GAPDH, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-GAPDH Antibody, Rabbit Polyclonal Validated Applications
| Application | Dilution |
|---|---|
| IHC-P | 1:1000-1:4000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-GAPDH Antibody, Rabbit Polyclonal Images
-HD09JA0406-0.5ug-renal-carcinoma-IHC-P.png)
Immunochemical staining of human GAPDH in human renal carcinoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
-HD09JA0406-0.5ug-hepatitis-IHC-P.png)
Immunochemical staining of human GAPDH in human hepatitis with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Anti-GAPDH Antibody, Rabbit Polyclonal: Synonyms
Anti-G3PD Antibody; Anti-GAPD Antibody; Anti-HEL-S-162eP Antibody
GAPDH Background Information
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer"s disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson"s disease, binds to GAPDH and displays neuroprotective actions.
Full Name
glyceraldehyde-3-phosphate dehydrogenase
Research Areas
- Adaptor Proteins
References
- Hara MR, et al. (2006) Neuroprotection by pharmacologic blockade of the GAPDH death cascade. PNA. 103 (10): 3887-9.
- Hara MR, et al. (2006) GAPDH as a sensor of NO stress.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1762 (5): 502-9.
- Tarze A, et al. (2007) GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilizationGAPDH and apoptosis. Oncogene. 26: 2606-20.
- Yi MK, et al. (2000) Functional Significance of the Interaction of Hepatitis A Virus RNA with Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH): Opposing Effects of GAPDH and Polypyrimidine Tract Binding Protein on Internal Ribosome Entry Site Function. Journal of Virology. 74 (14) : 6459-68.
- Clusterin role in hepatocellular carcinoma patients treated with oxaliplatin Short title: CLU in HCCAuthorWang, X;Liu, Y;Qin, Q;Zheng, T;Year2020Journalportlandpress.comFoldedExpand
- Clusterin role in hepatocellular carcinoma patients treated with oxaliplatinAuthorWang, X;Liu, Y;Qin, Q;Zheng, T;Year2020JournalBiosci. Rep.PubMed ID: 32039450FoldedExpand
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品牌介绍
北京义翘神州科技股份有限公司（Sino Biological Inc.）是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务。义翘神州为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。公司目前生产和销售的现货产品种类超过 4.6 万种，其中重组蛋白约 6,000 种，包括超过 3,800 种人源细胞表达重组蛋白产品，能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求；公司还能提供约 12,000 种抗体，其中单克隆抗体数量约 4,600 种，能够覆盖生命科学研究的多个领域，为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供「一站式」生物试剂产品和技术服务。义翘神州的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司，已成为生物试剂行业国内领先的科技公司之一。
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